Xue, Changhu

Chang-Hu Xue

Position:Dean, Professor, PhD. tutor

Major:Aquatic Products Processing and Storage Engineering

Gender: Male

Date of Birth: Nov. 25, 1964


Address:College of Food Science and Engineering, OceanUniversity of China, Qingdao 266003, China.


Fax: +86-532-82032468

E-mail: xuech@ouc.edu.cn


※1984.9-1990.7 M.S. and Ph.D., College of Food Science and Engineering, Ocean University of China Ocean University of China, Qingdao, China.

Major: Aquatic Products Processing and Storage Engineering

※1980.9-1984.7 B.S., College of Food Science and Engineering, OceanUniversity of ChinaOceanUniversity of China, Qingdao, China.

Major: Aquatic Products Processing and Storage Engineering


1990- Professor, Tutor of PhD student,Taishan ScholarDistinguished Professorof Aquatic Products Processing and Storage Engineering, College of Food Science and Engineering, Ocean University of China. P.R.China.

1994.10-1995.10Visiting Scholar, College of Agriculture, KyotoUniversity. Japan.

1999.1-2000.1 Postdoc., Fisheries Research Institute ofthe Ministry of Agriculture, Forestry and Fisheries of Japan.Japan.


Chief committee, Branch of Aquatic Products Processing and Comprehensive Utilization.

Secretary-general, Sea cucumber branch,China Association of Circulation and Processing of Aquatic Products.


Aquatic chemistry and products processing

High performance utilization of marine fisheries

Bioactive components and their bio-structure relationship of marine fisheries


Professor Xue has published more than 300 manuscripts including more than 70 in SCI journals. He has applied for more than 60 national invention patents, obtained more than 20 authorizations for invention patents, and 7 identifications of Provincial Technological Achievements. His research is supported by National Marine Public Welfare Scientific Research Project of China, International science & technology cooperation program of China, National Natural Science Foundation of China, Program for Changjiang Scholars and Innovative Research Team in University. Professor Xue is also the recipient of numerous awards, includingthe 2010 National Science and Technology Progress Award, the 2009 Science and Technology Progress Award from Ministry of Education of P.R.China, the 2009 Fanli Science and Technology Progress Award from China Society of Fisheries, and the 2007 China Agricultural Science and Technology Award from Agriculture Ministry of P.R.China.

Selected Publications in Recent Five Years:

1.YanchaoWang, Yaoguang Chang1, Long Yu, Cuiyu Zhang, Xiaoqi Xu, Yong Xue, Zhaojie Li, Changhu Xue∗. Crystalline structure and thermal property characterization of chitin fromAntarctic krill (Euphausia superba). Carbohydrate Polymers. 92, (2013) ,90-97

2.Lili Zhang , Yong Xue , Jie Xu, Zhaojie Li, Changhu Xue. Effects of high-temperature treatment (100°C) on Alaska Pollock (Theragra chalcogramma) surimi gels. Journal of Food Engineering. 115,(2013) ,115-120

3.Shiguo Chen , Guoyun Li, Nian Wu a, Xin Guo a, Ningbo Liao a, Xingqian Ye⁎, Donghong Liu, Changhu Xue b**, Wengang Chai. Sulfation pattern of the fucose branch is important for the anticoagulant and antithrombotic activities of fucosylated chondroitin sulfates. Biochimica et Biophysica Acta. 1830,(2013),3054-3066

4.Haihua Cong , Fang Liu , Zhongwei Tang , Changhu Xue. Dielectric properties of sea cucumbers (Stichopus japonicus) and model foods at 915 MHz. Journal of Food Engineering. 109,(2012), 635-639

5.Qiao-Ming Lou, Yu-Ming Wang, Xiao-Fang Liu and Chang-Hu Xue. LIPID PROFILE AND FATTY ACID COMPOSITIONS IN BODY WALL OF APOSTICHOPUS JAPONICUS (SELENKA). Journal of Food Biochemistry. 36,(2012), 317-321

6.Shiguo Chen, Yaqin Hu, Xinqian Ye , Guoyun Li, Guangli Yu , Changhu Xue b*, Wengang Chai⁎. Sequence determination and anticoagulant and antithrombotic activities of a nove sulfated fucan isolated from the sea cucumber Isostichopus badionotus. Biochimica et Biophysica Acta .1820,(2012),989-1000

7.Xiaofang Liu, Changhu Xue*, Yuming Wang, Zhaojie Li, Yong Xue, Jie Xu. The classification of sea cucumber (Apostichopus japonicus) according to region of origin using multi-element analysis and pattern recognition techniques. Food Control. 23,(2012), 522-527

8.Lingzhao Wang,Changhu Xue,*Yuming Wang,and Bao Yang. Extraction of Proteins with Low Fluoride Level from Antarctic Krill (Euphausia superba) and Their Composition Analysis. Journal of food engineering. 59,(2011),6108-6112

9.Guoyun Li, Shiguo Chen, Yuming Wang, Yong Xue, Yaoguang Chang, Zhaojie Li , Jingfeng Wang, Changhu Xue∗. A novel glycosaminoglycan-like polysaccharide from abalone Haliotis discus hannai Ino: Purification, structure identification and anticoagulant activity. International Journal of Biological Macromolecules. 49, (2011),1160-1166

10.Jie Xu, Jingjing Duan, Changhu Xue* ,Tingyu Feng,Ping Dong,Tatsuya Sugawara,and Takashi Hirata. Analysis and Comparison of Glucocerebroside Species from ThreeEdibleSea Cucumbers Using Liquid Chromatography_Ion Trap_Time-of-Flight Mass Spectrometry. Journal of Agricultural and Food Chemistry. 59, (2011),12246-12253

11.Shiguo Chen, Changhu Xue∗,Li’ang Yin, Qingjuan Tang, Guangli Yu, Wengang Chai∗.Comparison of structures and anticoagulant activities of fucosylated chondroitin sulfates from different sea cucumbers.Carbohydrate Polymers. 83, (2011), 688-696

12.Qin ZHAO, Zhi-dong LIU, Yong XUE, Jing-feng WANG,Hui LI, Qing-juan TANG, Yu-ming WANG, Ping DONG, Chang-hu XUE*. Ds-echinoside A, a new triterpene glycoside derived from sea cucumber, exhibits antimetastatic activity via the inhibition of NF-κB-dependent MMP-9 and VEGF expressions. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology).12,(2011),534-544

13.Jie Xv*,Yu-Ming Wang*,Ting-Yu Feng, Bei Zhang,Tatsuya Sugawara,Chang-HU Xue*.Isolation and Anti-Fatty Liver Activity of a Novel Cerebroside from the Sea Cucumber Acaudina molpadiosdes. Biosci.Biotechnol.Biochen. 75, (2011),1466-1471

14.Yu-Ming Wang , Xiao-Qian Hu,Yong Xue , Zhao-Jie Li ,Teruyoshi Yanagita , Chang-Hu Xue*.Study on possible mechanism of orotic acid–induced fatty liver in rats. Nutrition. 27,(2011), 571-575

15.Xiao-Qian Hu, Yu-Ming Wang, Jing-Feng Wang, Yong Xue, Zhao-Jie Li1, Koji Nagao, Teruyoshi Yanagita, Chang-Hu Xue*. Dietary saponins of sea cucumber alleviate orotic acid-induced fatty liver in rats via PPARa and SREBP-1c signaling.Lipids in Health and Disease. 9,(2010), 25

16.Y. Chang, C. Xue, Q. Tang, D. Li, X. Wu and J. Wang, Chang-Hu Xue*. Isolation and characterization of a sea cucumber fucoidanutilizing marine bacterium. Letters in Applied Microbiology. 50,(2010), 301-307

17.Shiguo Chen, Jingfeng Wang, Changhu Xue∗, Hui Li, Beibei Sun, Yong Xue, Wengang Chai. Sulfation of a squid ink polysaccharide and its inhibitory effect on tumor cell metastasis. Carbohydrate Polymers. 81, (2010), 560-566

18.Yu-Ming Wang, Bei Zhang, Yong Xue, Zhao-Jie Li, Jing-Feng Wang, Chang-Hu Xue*, Teruyoshi Yanagita The mechanism of dietary cholesterol effects on lipids metabolism in rats. Lipids in Health and Disease. 9,(2010), 4

19.Qingjuan Tang , Dan Li , Jie Xu ,Jingfeng Wang, Yuran Zhao, Zhaojie Li, Changhu Xue*. Mechanism of inactivation of murine norovirus-1 by high pressure processing. International Journal of Food Microbiology. 137,(2010), 186-189

20.Rong Cao,Chang-hu Xue*,Qi Liu. Changes in microbial flora of Pacific oysters (Crassostrea gigas) during refrigerated storage and its shelf-life extension by chitosan. International Journal of Food Microbiology. 131, (2009), 272-276

21.Dan Li, Qingjuan Tang, Jingfeng Wang, Yuming Wang, Qin Zhao, Changhu Xue*. Effects of high-pressure processing on murine norovirus-1 in oysters(Crassostrea gigas) in situ.Food Control. 20,(2009),992-996

22.Qi-Long Shi ,Ya Zhao, Hai-Hua Chen,Zhao-Jie Li ,Chang-Hu Xue*. Glass transition and state diagram for freeze-dried horse mackerel muscle. Thermochimica Acta. 493,(2009),55-60

23.Feng Li , Hong-ying Liu,Chang-hu Xue∗, Xue-qian Xina, Jie Xua, Yao-guang Chang, Yong Xue, Li-ang Yina. Simultaneous determination of dimethylamine, trimethylamine and trimethylamine-n-oxide in aquatic products extracts by ion chromatography with non-suppressed conductivity detection. Journal of Chromatography A. 1216,(2009),5924-5926