Mao, Xiangzhao



Xiangzhao Mao

 

Professor, Department of Food Science and Engineering, Ocean University of China, Qingdao, Shandong 266003, China; Tel: 86-532-8203-2660; Email: xzhmao@ouc.edu.cn

Education and Training

2003-2008 Ph.D. State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, P.R.China

1999-2003 B.S. School of Life Science, Shandong University , P.R.China.

Appointment

2010—now Department of Food Science and Engineering, Ocean University of China

2008-2010 Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences

Research Abstract:

Aquatic Product Processing with Biotechnology: Processing the aquatic product and byproduct to seafood and bioactive compound with fermentation, biocatalysis and biotransformation technology.

Marine Enzyme and Biocatalysis mechanism: Discovery of novel marine enzymes and enzymatic reactions in the processing of aquatic product. Direct evolution of enzyme in vitro, creating better tools for new biocatalyst development.

Synthetic Biology and Systematic Metabolic Engineering of Marine Bioactive Compounds: Redesigning and regulation of pathway to produce marine bioactive compounds by metabolic engineering and synthetic biology.

Research programs in recent years:

National Science Foundation of China:

Study on the molecular biology and catalytic function of the dextran dextrinase from Gluconobacter oxydans

National Science Foundation of China:

Molecular Modification of Novel β-Agarase, and the Mechanism of the Rational Regulation for the Degree of Polymerization of Neoagarooligosaccharides

National Science Foundation of China:

Molecular mechanism of odd-number agarooligosaccharides formation by α-neoagarobinose hydrolase and the structure-function relationship of products

National Modern Agricultural Industry Technology System Program:

Comprehensive utilization of shrimp and crab byproducts

Teaching Activity

Biochemical Reaction Engineering

Bioengineering Equipment

Honors   received

The Second Prize for Science & technology Development of the Ministry of Education (2017, No. 1)

The Second Prize for Ocean Engineering Science and Technology Award (2017, No. 1)

The First Prize for Progress in Science and technology of Qingdao（2016, No. 1）

Selected Publications:

1. Li Gao, Jianan Sun, Francesco Secundo, Xin Gao, Changhu Xue, Xiangzhao Mao*. Cloning, characterization and substrate degradation mode of a novel chitinase from Streptomyces albolongus ATCC 27414. Food Chemistry, 2018, 261: 329-336

2. Wen-Can Huang#, Wei Wang#, Changhu Xue, Xiangzhao Mao*. Effective enzyme immobilization onto a magnetic chitin nanofiber composite. ACS Sustainable Chemistry & Engineering, 2018, 6: 8118-8124

3. Wen-Can Huang#, Dandan Zhao#, Na Guo, Changhu Xue, Xiangzhao Mao*. Green and facile production of chitin from crustacean shells using a natural deep eutectic solvent. Journal of Agricultural and Food Chemistry, 2018, 66, 11897-11901

4. Qidong Wang, Jianan Sun, Zhen Liu, Wen-Can Huang, Changhu Xue, Xiangzhao Mao*. Co-immobilization of β-agarase and α-neoagarobiose hydrolase for enhancing the production of 3,6-anhydro-L-galactose. Journal of Agricultural and Food Chemistry, 2018, 66: 7087-7095

5. Ping Lu, Xinwei Gao, Hao Dong, Zhen Liu, Francesco Secundo, Changhu Xue, Xiangzhao Mao*. Identification of a novel esterase from marine environmental genomic DNA libraries and its application in production of free all-trans-astaxanthin. Journal of Agricultural and Food Chemistry, 2018, 66:2812-2821

6. Xiaoqing Yang, Zhen Liu, Chengcheng Jiang, Jianan Sun, Changhu Xue, Xiangzhao Mao*. A novel agaro-oligosaccharide-lytic β-galactosidase from Agarivorans gilvus WH0801. Applied Microbiology and Biotechnology, 2018, 102(12): 5165-5172

7. Wen-Can Huang, Hui Liu, Weiwei Sun, Changhu Xue, Xiangzhao Mao*. Effective astaxanthin extraction from wet Haematococcus pluvialis using switchable hydrophilicity solvents. ACS Sustainable Chemistry & Engineering, 2018, 6 (2): 1560-1563

8. Yating Zhang, Zhen Liu, Jianan Sun, Changhu Xue, Xiangzhao Mao*. Biotechnological production of zeaxanthin by microorganisms. Trends in Food Science & Technology, 2018, 71: 225-234

9. Xiangzhao Mao*, Zhen Liu, Jianan Sun, Sang Yup Lee*. Metabolic engineering for the microbial production of marine bioactive compounds. Biotechnology Advances, 2017, 35: 1004-1021

10. Yunxiao Liang, Xiaoqing Ma, Lujia Zhang, Fuli Li, Zhen Liu,  Xiangzhao Mao*. Biochemical characterization and substrate degradation mode of a novel exo-type β-agarase from Agarivorans gilvus WH0801. Journal of Agricultural and Food Chemistry, 2017, 65 (36): 7982-7988

11. Bohuan Fang, Jianan Sun, Ping Dong, Changhu Xue, Xiangzhao Mao*. Conversion of turbot skin wastes into valuable functional substances with an eco-friendly fermentation technology. Journal of Cleaner Production, 2017, 156: 367-377

12. Hao Dong, Francesco Secundo, Changhu Xue, Xiangzhao Mao*. Whole-cell biocatalytic synthesis of cinnamyl acetate with a novel esterase from the DNA library of acinetobacter haemolyticus. Journal of Agricultural and Food Chemistry, 2017: 65 (10), 2120-2128

13. Xiangzhao Mao#,*, Na Guo#, Jianan Sun, Changhu Xue. Comprehensive utilization of shrimp waste based on biotechnological methods: A Review. Journal of Cleaner Production, 2017, 143: 814-823

14. Jianan Sun, Xiangzhao Mao*. An environmental friendly process for antarctic krill (euphausia superba) utilization using fermentation technology. Journal of Cleaner Production, 2016, 127, 618-623

15. Pei Liu, Shanshan Liu, Na Guo, Xiangzhao Mao*, Hong Lin, Changhu Xue, Dongzhi Wei. Cofermentation of Bacillus licheniformis and Gluconobacter oxydans for chitin extraction from shrimp waste. Biochemical Engineering Journal, 2014, 91(15): 10-15