Marine Biological Substance Lab
Description
The long-term goals of our research programs include 1) food source derived bio-functional substances, such as bioactive peptides, collagen, glycoproteins and flavonoids, from marine biological resources; 2) utilization of the aquatic processing byproducts; 3) development of functional food ingredients and functional foods. The research schematic in our current projects includes purification and identification approach, structure-activity relationship, in vitro cell culture and in vivo animal study.
Location and contact
The laboratory is located in room 112 of the LiuerBuilding. Contact us by phone: +86 0532-82031936.
Faculty in this lab
1.Prof. Bafang Li
Marine Biological Substance
Tel.:0532-82031852; E-mail: bfli@ouc.edu.cn
2.Prof. Zhaohui Zhang
Food chemistry and food flavor chemistry.
Tel.: 0532-82031936; E-mail: Zhangzhh@ouc.edu.cn
3.Prof. Xue Zhao
Marine Biological Substance
Tel.: 0532-82031936; E-mail: zhaoxue@ouc.edu.cn
4.Dr. Hu Hou
Marine Biological Substance
Tel.: 0532-82031936; E-mail: houhu@ouc.edu.cn
Lab publications
1.CHEN, A., ZHANG, F., SHI, J. & ZHAO, X. 2012. Study on antithrombotic and antiplatelet activities of low molecular weight fucoidan from Laminaria japonica. Journal of OceanUniversity of China, 11, 236-240.
2.GUO, L., HOU, H. & LI, B. 2013. Preparation, isolation and identification of iron-chelating peptides derived from Alaska pollock skin. Process Biochemistry, 48, 988-993.
3.HOU, H., FAN, Y., LI, B., XUE, C. & YU, G. 2012. Preparation of immunomodulatory hydrolysates from Alaska pollock frame. J Sci Food Agric, 92, 3029-38.
4.HOU, H., FAN, Y., LI, B., XUE, C., YU, G., ZHANG, Z. & ZHAO, X. 2012. Purification and identification of immunomodulating peptides from enzymatic hydrolysates of Alaska pollock frame. Food Chem, 134, 821-8.
5.LIN, L. & LI, B.-F. 2006. Radical scavenging properties of protein hydrolysates from Jumbo flying squid (Dosidicus eschrichitii Steenstrup) skin gelatin. Journal of the Science of Food and Agriculture, 86, 2290-2295.
6.LIN, L., LV, S. & LI, B. 2012. Angiotensin-I-converting enzyme (ACE)-inhibitory and antihypertensive properties of squid skin gelatin hydrolysates. Food Chemistry, 131, 225-230.
7.REN, G., LI, B., ZHAO, X., ZHUANG, Y., YAN, M., HOU, H., ZHANG, X. & CHEN, L. 2009. Screening of extraction methods for glycoproteins from jellyfish (Rhopilema esculentum) oral-arms by high performance liquid chromatography. Journal of OceanUniversity of China, 8, 83-88.
8.WANG, S., HOU, H., HOU, J., TAO, Y., LU, Y., YANG, X. & LI, B. 2012. Characterization of Acid-Soluble Collagen From Bone of Pacific Cod (Gadus macrocephalus). Journal of Aquatic Food Product Technology, 22, 407-420.
9.YAN, M., LI, B. & ZHAO, X. 2010. Determination of critical aggregation concentration and aggregation number of acid-soluble collagen from walleye pollock (Theragra chalcogramma) skin using the fluorescence probe pyrene. Food Chemistry, 122, 1333-1337.
10.HOU, H., LI, B., ZHANG, Z., XUE, C., YU, G., WANG, J., BAO, Y., BU, L., SUN, J., PENG, Z. & SU, S. 2012. Moisture absorption and retention properties, and activity in alleviating skin photodamage of collagen polypeptide from marine fish skin. Food Chem, 135, 1432-9.
11.HOU, H., LI, B. & ZHAO, X. 2011. Enzymatic hydrolysis of defatted mackerel protein with low bitter taste. Journal of OceanUniversity of China, 10, 85-92.
12.YAN, M., LI, B., ZHAO, X., REN, G., ZHUANG, Y., HOU, H., ZHANG, X., CHEN, L. & FAN, Y. 2008. Characterization of acid-soluble collagen from the skin of walleye pollock (Theragra chalcogramma). Food Chemistry, 107, 1581-1586.
13.YAN, M., LI, B., ZHAO, X. & YI, J. 2011. Physicochemical properties of gelatin gels from walleye pollock (Theragra chalcogramma) skin cross-linked by gallic acid and rutin. Food Hydrocolloids, 25, 907-914.
14.ZHANG, Z., GAO, X., YURI, T. & OGAWA, H. 2005. Determination of selenium in marine aquatic products by hydride generation-atomic fluorescence spectrometry (HG-AFS). Journal of OceanUniversity of China, 4, 252-256.
15.ZHANG, Z., GAO, X., YURI, T., SHINGO, M. & HIROO, O. 2004. Researches on the stability of porphyra-334 solution and its influence factors. Journal of OceanUniversity of China, 3, 166-170.
16.ZHAO, X., DONG, S., WANG, J., LI, F., CHEN, A. & LI, B. 2012a. A comparative study of antithrombotic and antiplatelet activities of different fucoidans from Laminaria japonica. Thrombosis Research, 129, 771-778.
17.ZHAO, X., XUE, C.-H., LI, Z.-J., CAI, Y.-P., LIU, H.-Y. & QI, H.-T. 2004. Antioxidant and hepatoprotective activities of low molecular weight sulfated polysaccharide from Laminaria japonica. Journal of Applied Phycology, 16, 111-115.
18.HOU, H., LI, B., ZHAO, X., ZHANG, Z. & LI, P. 2011. Optimization of enzymatic hydrolysis of Alaska pollock frame for preparing protein hydrolysates with low-bitterness. LWT - Food Science and Technology, 44, 421-428.
19.HOU, H., LI, B., ZHAO, X., ZHUANG, Y., REN, G., YAN, M., CAI, Y., ZHANG, X. & CHEN, L. 2009. The effect of pacific cod (Gadus macrocephalus) skin gelatin polypeptides on UV radiation-induced skin photoaging in ICR mice. Food Chemistry, 115, 945-950.
20.ZHAO, X., YANG, B., DATTA, P., GASMILI, L., ZHANG, F. & LINHARDT, R. J. 2012b. Cell-Based Microscale Isolation of Glycoaminoglycans for Glycomics Study. J Carbohydr Chem, 31, 420-435.
21.ZHAO, X., YANG, B., LI, L., ZHANG, F. & LINHARDT, R. J. 2013a. On-line separation and characterization of hyaluronan oligosaccharides derived from radical depolymerization. Carbohydrate Polymers, 96, 503-509.
22.ZHAO, X., YANG, B., LINKENS, K., DATTA, P., ONISHI, A., ZHANG, F. & LINHARDT, R. J. 2013b. Microscale separation of heparosan, heparan sulfate, and heparin. Analytical Biochemistry, 434, 215-217.
23.ZHAO, X., YANG, B., LINKENS, K., DATTA, P., ONISHI, A., ZHANG, F. & LINHARDT, R. J. 2013c. Microscale separation of heparosan, heparan sulfate, and heparin. Anal Biochem, 434, 215-7.
24.26.ZHAO, X., YANG, B., SOLAKYILDIRIM, K., JOO, E. J., TOIDA, T., HIGASHI, K., LINHARDT, R. J. & LI, L. 2013d. Sequence analysis and domain motifs in the porcine skin decorin glycosaminoglycan chain. J Biol Chem, 288, 9226-37.
25.HOU, H., ZHAO, X., LI, B., LI, P., ZHANG, Z., SHAO, X., PANG, W. & QU, X. 2012. Solid-Phase Microextraction Method for the Determination of Volatile Compounds in Hydrolysates of Alaska Pollock Frame. International Journal of Food Properties, 16, 790-802.
26.HOU, H. U., ZHAO, X. U. E., LI, B., ZHANG, Z. & ZHUANG, Y. 2011. INHIBITION OF MELANOGENIC ACTIVITY BY GELATIN AND POLYPEPTIDES FROM PACIFIC COD SKIN IN B16 MELANOMA CELLS. Journal of Food Biochemistry, 35, 1099-1116.
27.ZHUANG, Y., HOU, H., ZHAO, X., ZHANG, Z. & LI, B. 2009a. Effects of collagen and collagen hydrolysate from jellyfish (Rhopilema esculentum) on mice skin photoaging induced by UV irradiation. J Food Sci, 74, H183-8.
28.ZHUANG, Y., SUN, L., ZHAO, X., WANG, J., HOU, H. & LI, B. 2009b. Antioxidant and melanogenesis-inhibitory activities of collagen peptide from jellyfish (Rhopilema esculentum). Journal of the Science of Food and Agriculture, 89, 1722-1727.
Lab photos
Current and past lab students, postdocs
Ongoing Ph.D students:
1st year student: Qianru Chen
2nd year student: Hongwei Zhang
3rd year student: Lidong Guo, Huicheng Yang, Yuran Zhao, Hai Huang
Ongoing master students:
1st year student: Huina Niu, Haixu Zheng, Jing Hu, Jing Li, Fen Du, Tiejun Chen, Shumei Zhang, Miaomiao Zhang
2nd year student: Yufei Chang, Ming Xie, Lin Bu, Ming Guo, Xing Li, Meiying Niu, Xueying Wang, Ming Gao,
3rd year student: Jingsha Sun, Huiming Jiang, Fengjun Guo, Weiwei Li
Graduate students:
Ph.D:
Shanshan Wang, Ying Wang (2013), Yangpeng Cai (2011), Yongliang Zhuang (2009).
Master:
2013: Xia Yang, Zhicong Wang, Jingfeng Wang, Yukun Lu, Jie Hou, Yufeng Wang.
2012: Fuchai Zhao, Yu Tao, Fang Li, Ningning Jin, Lulu Liu.
2011: Lijuan Gao, Xiaomin Shao, Guo Li, Yuming Bao, Zhijuan Liu.
