Name: Jianfeng Zhou
Address: Minxing Building, Ocean University of China,
#5 Yushan Road, Qingdao 266003
Tel.: 86-532-82032957
E-mail: jfzhou@ouc.edu.cn
Education:
Ph.D. 2004 Institute of Hydrobiology, Chinese Academy of Sciences
B.S. 1998 Department of Biology, Hebei University
Professional Experience:
2009-present Professor, School of Medicine and Pharmacy, Ocean University of China
2006-2008Postdoctoral Fellow/Visiting Scholar, Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor
2004-2006Research Assistant Professor/Research Associate Professor, Wuhan Botanical Garden, Chinese Academy of Sciences
Research Interest:
1) basic biology of molecular medicine; 2) roles of biomolecules in regulating development, growth, reproduction, and aging; 3) establishment of animal models of human disease; 4) chemical biology and compound screening by using zebrafish.
Awardsandhonors:
2009 ProgramforNewCenturyExcellentTalentsinUniversity (MOE, China).
Recent publication:
1.Bai Y, Liu C, Zhang H, Li Y, Lu L, Liu Y, Zhou J#. (2014) Ror2 mediates Wnt11 signaling and affects convergence and extension movements in zebrafish.In revision.
Rong X*, Chen C*,Zhou P, Zhou Y,Li Y, Lu L, Liu Y, Zhou J#, Duan C# (2014) R-spondin 3 regulates dorsoventral patterning and anteroposterior formation by antagonizing Wnt/β-catenin signaling pathway in zebrafish embryos. In revision.
2.Liu C, Luan J, Bai Y, Li Y, Lu L, Liu Y, Hakuno F, Takahashi S, Duan C, Zhou J#. (2014) Aspp2 negatively regulates body growth but not developmental timing by modulating IRS signaling in zebrafish embryos.Gen Comp Endocrinol. 197:82-91.
3.Zhou J, Xiang J, Zhang S, Duan C. (2013) Structural and functional analysis of the amphioxus IGFBP gene uncovers ancient origin of IGF-independent functions.Endocrinology154(10):3753-63.
Kjaer-Sorensen K, Engholm DH, Kamei H, Morch MG, Kristensen AO, Zhou J, Conover CA, Duan C, Oxvig C. (2013) Pregnancy-associated plasma protein A (PAPP-A) modulates the early developmental rate in zebrafish independently of its proteolytic activity.J Biol Chem. 288(14):9982-92.
4.Feng Q, Zou X, Lu L, Li Y, Liu Y, Zhou J#, Duan C#. (2012) The stress-response gene redd1 regulates dorsoventral patterning by antagonizing Wnt/β-catenin activity in zebrafish.PLoS One 7(12):e52674.
5.Jiao S, Ren H, Li Y, Zhou J, Duan C, Lu L. (2013) Differential regulation of IGF-I and IGF-II gene expression in skeletal muscle cells.Mol Cell Biochem. 373(1-2):107-13.
6.Zhang P, Lu L, Yao Q, Li Y, Zhou J, Liu Y, Duan C. (2012) Molecular, functional, and gene expression analysis of zebrafish hypoxia-inducible factor-3α.Am J Physiol Regul Integr Comp Physiol. 303(11):R1165-74.
7.Zhang C, Lu L, Li Y, Wang X, Zhou J, Liu Y, Fu P, Gallicchio MA, Bach LA, Duan C. (2012) IGF binding protein-6 expression in vascular endothelial cells is induced by hypoxia and plays a negative role in tumor angiogenesis.Int J Cancer. 130(9):2003-12.
8.Zhong Y, Lu L, Zhou J, Li Y, Liu Y, Clemmons DR, Duan C. (2011) IGF binding protein 3 exerts its ligand-independent action by antagonizing BMP in zebrafish embryos.J Cell Sci. 124:1925-35.
9.Jiao S, Dai W, Lu L, Liu Y, Zhou J, Li Y, Korzh V, Duan C. (2011) The conserved clusterin gene is expressed in the developing choroid plexus under the regulation of notch but not IGF signaling in zebrafish.Endocrinology152:1860-71.
10.Zhou J, Li W, Kamei H, Duan C. (2008) Duplication of the IGFBP-2 gene in teleost fish: protein structure and functionality conservation and gene expression divergence.PLoS One 3(12):e3926.
