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Hongbing Liu Professor of Marine Traditional Chinese Medicine Address: Key Laboratory of Marine Drugs, Ministry of Education Marine Drug and Food Institute, School of Medicine and Pharmacy, Ocean University of China, 5 Yushan Road, Qingdao, 266003, China Tel: 86-532-82031823Fax: 86-532-82033054 E-Mail:liuhongb@mail.ouc.edu.cn EducationPh.D. 2004School of Medicine and Pharmacy, Ocean University of China M.S. 1996School of Traditional Chinese Medicine, Shenyang Pharmaceutical University B.S. 1993Department of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine
Professional Experience:2015-present Professor, School of Medicine and Pharmacy, Ocean University of China 2006-2015 Associate Professor, School of Medicine and Pharmacy, Ocean University of China 2005-2006 Postdoctoral Fellow/Visiting Scholar, Institute of Pharmaceutical Biology, Heinrich- Heine- University, Germany
Research Interests:1. Isolation and identification of active constituents in marine Traditional Chinese Medicine (TCM), especially focusing on marine algae. 2. Lipidomics research on marine TCM Sargassum (海藻”Haizao”). 3. Quality control of marine TCM. 4. R&D of marine traditional Chinese classics prescriptions. PublicationsWang Dao-Liang, Sowemimo Abimbola, Gu Yu-Chao, Gao Shang, Liu Hong-Bing *, Proksch Peter. Enterolacaciamine as a potential O-GlcNAcase activator from the leaves of Enterolobium cyclocarpum. Fitoterapia, 2015, 105: 89-92. Ma Aicui, Chen Zhen, Wang Tao, Song Ni, Yan Qian, Fang Yuchun, Guan Huashi, Liu Hongbing*. Isolation of the Molecular Species of Monogalactosyldiacylglycerols from Brown Edible Seaweed Sargassum horneri and Their Inhibitory Effects on Triglyceride Accumulation in 3T3-L1 Adipocytes. J. Agri. Food Chem.2014, 62 (46): 11157-11162 Zhen Chen, Jiao Liu, Zhifei Fu, Cheng Ye, Renshuai Zhang, Yiyun Song, Ying Zhang, Haihua Li, Hao Ying*, Hongbing Liu*. 24(S)-Saringosterol from Marine Edible Seaweed Sargassum fusiforme is a Novel Selective LXRβ Agonist. J. Agir. Food Chem. 2014, 62 (26): 6130-6137. HE Shan, LIU Hongbing*, YANG Xue, LI Chunxia, and GUAN Huashi*. What Depth Should Deep-Sea Water be Pumped up from in the South China Sea for Medicinal Research? J. Ocean Univ. China 2013, 12 (1): 134-138. Xue Yang, Shi-Lu Zhou, Ai-Cui Ma, Hai-Tao Xu, Hua-Shi Guan,* and Hong-Bing Liu*. Chemical Profiles and Identification of Key Compound Caffeine in Marine-Derived Traditional Chinese Medicine Ostreae concha. Mar. Drugs 2012, 10, 1180-1191. Hongbing Liu, RuAngelie Edrada-Ebel, Rainer Ebel, Yao Wang, Barbara Schulz, Siegfried Draeger, Werner E. G. Muller, Victor Wray, Wenhan Lin, and Peter Proksch. Ophiobolin Sesterterpenoids and Pyrrolidine Alkaloids from the Sponge Derived Fungus Aspergillus ustus. Helvetica Chimica Acta. 2011, 94(4): 623-631. Dengzhao Jiang, Xue Yang, Hongbing Liu* and Huashi Guan*. Development and validation of a high performance liquid chromatographic method for the determination of stemoninine in rat plasma after administration of Stemona tuberosa extracts. Biomed. Chromatogr.2011, 25:498-502. Hongbing Liu, RuAngelie Edrada-Ebel, Rainer Ebel, Yao Wang, Barbara Schulz, Siegfried Draeger, Werner E. G. Muller,| Victor Wray, Wenhan Lin, and Peter Proksch. Drimane Sesquiterpenoids from the Fungus Aspergillus ustus Isolated from the Marine Sponge Suberites domuncula. J. Nat. Prod. 2009, 72(9): 1585-1588. Xian-Jun Fu, Hong-Bing Liu, Peng Wang and Hua-Shi Guan. A Study on the Antioxidant Activity and Tissues Selective Inhibition of Lipid Peroxidation by Saponins from the Roots of Platycodon grandiflorum. The American Journal of Chinese Medicine. 2009, 37(5): 967-975. Fuquan Xu, Huashi Guan, Guoqiang Li, Hongbing Liu.LC Method for Analysis of Three Flavonols in Rat Plasma and Urine after Oral Administration of Polygonum aviculare Extract. Chromatographia. 2009, 69(11/12): 1251-1258. Du Lin, Zhu Tianjiao, Liu Hongbing, Fang Yuchun, Zhu Weiming, and Gu Qianqun. Cytotoxic Polyketides from a Marine-derived Fungus Aspergillus glaucus. J. Nat. Prod. 2008, 71, 1837–1842. Peter Proksch, Rainer Ebel, RuAngelie Edrada, Frank Riebe, Hongbing Liu, Arnulf Diesel, Mirko Bayer, Xiang Li, Wen Han Lin, Vladislav Grebenyuk, Werner E. G. Müller, Siegfried Draeger, Alga Zuccaro and Barbara Schulz. Sponge-associated fungi and their bioactive compounds: the Suberites case. Botanica Marina 2008, 51: 209–218.
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