FACULTY

Pinglin Li

Author：蔡超Time：2019-11-22

Pinglin LI

Ph.D.

Professor

Ph.D. supervisor

Department:

Marine natural medicine

Phone：

86-532-82031905

Email:

lipinglin@ouc.edu.cn

Address:

School of Medicine and Pharmacy, Room 130, No. 5 Yushan Road, Qingdao, Shandong, 266003

Research Area:

We are mainly focusing onsmall molecules from marine organisms (coral, sponge, symbioticmicroorganismsetc.), including of targeted isolation of the compounds, structural identification of NPs, structure-activity relationship, and the original study of NPs and their big-scale production.

Biography

 

 

 

 

 

Education

 

 

 

 

2015.09~2016.09

Scripps Institution of Oceanography UC San Diego

Marine natural products

Visiting scholar

2003.09~2008.07

Lanzhou University

Natural Products Chemistry

Ph.D.

1999.09~2003.06

Lanzhou University

Chemistry

B.S.

Work Experience

 

 

 

 

2016.01~Present

School of Medicine and Pharmacy, Ocean University of China

Professor

 

2014.01~2015.12

School of Medicine and Pharmacy, Ocean University of China

Associate Professor

 

2011.01~2013.12

School of Medicine and Pharmacy, Ocean University of China

Lecturer

 

2008.07~2011.01

College of Food Science and Engineering, Ocean University of China

Lecturer

 

Academic Acitivities

 

 

 

 

Member of Chinese Pharmaceutical Association

Honors

 

 

 

 

2015  Outstanding Young Scientist Fund

2016  Shandong Province Science Fund for Distinguished Young Scholars

Courses

 

 

 

 

Spectrometric Identification of Organic Compounds (for undergraduate)

Research Interests

 

 

 

Focusing on the structural diversity and broad-spectrum biological functions of new structural and functional molecules in marine sponges and corals, more than 600 compounds of various structural types were obtained, including 200 new compounds and 40 new skeleton compounds. Preliminary activity evaluation showed that dozens of compounds had strong cytotoxic, antifouling and antivirus activities. The preliminary results of the ongoing research on the utilization of sponges and corals in Xisha Islands prove that the biological resources of sponges and corals in the distant Xisha Islands are obviously different from those in the offshore areas, and have significant marine characteristics.

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Publications

 

 

 

 

Papers

 

 

 

 

  1. Xiao Han, Xiangchao Luo, Lei Xue, Leen van Ofwegen, Wenjie Zhang, Kechun Liu, Yun Zhang,Xuli Tang, PinglinLi,* and Guoqiang Li*. Dolabellane Diterpenes and Elemane Alkaloids from the Soft CoralClavulariainflata Collected in the South China Sea. J. Nat. Prod. 2022, 85, 276−283.

  2. TianyunJin, Pinglin Li*, Cili Wang, Xuli Tang, Xiaoli Yu, Fengqing Sun,Lianzhong Luo, HuilongOu, Guoqiang Li*. Jellynolide A, pokepola esters, and sponalisolides from the aquaculturesponge Spongia officinalis L. Phytochemistry,2022, 194, 113006.

  3. XiangchaoLuo,‡Rongcui Wu,‡ Xiao Han,‡ Xuli Tang, Qi Wang, Pinglin Li*and Guoqiang Li *. Guaiane sesquiterpenes from the gorgonianEchinogorgia flora collected in the South ChinaSea. RSC Adv., 2022, 12, 2662.

  4. Tian-Yun Jin,‡, Ping-Lin Li,‡,*, Ci-Li Wang, Xu-Li Tang, Mei-Mei Cheng, Yuan Zong, Lian-Zhong Luo, Hui-Long Ou, Ke-Chun Liu, and Guo-Qiang Li*. Racemic Bisindole Alkaloids: Structure, Bioactivity, and computational Study. Chin. J. Chem.2021, 39, 2588-2598.

  5. Xiangchao Luo, Qi Wang,* Xuli Tang, Jixiang Xu, Mengxue Wang, Pinglin Li,* and Guoqiang Li*. Cytotoxic Manoalide-Type Sesterterpenes from the SpongeLuffariella variabilis Collected in the South China Sea. J. Nat. Prod. 2021, 84, 61−70.

  6. MeimeiCheng,⊥Pinglin Li,*,⊥ Yun Jiang,⊥ Xuli Tang, Wenjie Zhang, Qi Wang,* and Guoqiang Li*. Penitol A and Penicitols E−I: Citrinin Derivatives from Penicilliumcitrinum and the Structure Revision of Previously ProposedAnalogues.J. Nat. Prod.2021, 84, 1345−1352.

  7. MingyuLiu,#Pinglin Li,*,#Xuli Tang, Xiangchao Luo, Kechun Liu, Yun Zhang, Qi Wang,*and Guoqiang Li*. Lemnardosinanes A‑I: New Bioactive Sesquiterpenoids from SoftCoral Lemnalia sp.J. Org. Chem. 2021, 86, 970−979.

  8. Qi Wang, Yanting Sun, Lin Yang, Xiangchao Luo, Nicole J. de Voogd, Xuli Tang,*Pinglin Li,*and Guoqiang Li*. BishomoscalaraneSesterterpenoids from the Sponge Dysidea granulosa Collected in the South China Sea. Journal of Natural Products, 2020, 83, 516-523.

  9. Qi Wang, Xuli Tang, Hui Liu, Xiangchao Luo, Ping Jyun Sung, Pinglin Li,*and Guoqiang Li*. Clavukoellians G–K, New Nardosinane andAristolane Sesquiterpenoids with AngiogenesisPromoting Activity from the Marine Soft CoralLemnalia sp.Marine Drugs, 2020, 18, 171.

  10. Tao Li, Xuli Tang, Xiangchao Luo, Qi Wang, Kechun Liu, Yun Zhang, Nicole J. de Voogd, Junjie Yang, Pinglin Li,* and Guoqiang Li*. Agelanemoechine, a Dimeric Bromopyrrole Alkaloid with a Pro-Angiogenic Effect from the South China Sea Sponge Agelasnemoechinata. Organic Letters, 2019, 21, 9483-9486.

  11. Jing Zhang, Xuli Tang, Xiao Han, Danqing Feng, Xiangchao Luo, Leen van Ofwegen, Pinglin Li* and Guoqiang Li *. Sarcoglaucins A-I, new antifouling cembrane-type diterpenes from the South China Sea soft coral Sarcophyton glaucum. Organic Chemistry Frontiers, 2019, 6, 2004-2013.

  12. Xingwang Zhang,#Ping-Lin Li,# Guo-Fei Qin, Shengying Li, Nicole J. de Voogd, Xu-Li Tang* and Guo-Qiang Li*. Isolation and Absolute Configurations of Diversiform C17, C21 and C25 Terpenoids from the Marine Sponge Cacospongia sp. Marine Drugs, 2019, 17, 1-14.

  13. Yiwen Tao,#Pinglin Li,#Daojing Zhang, Evgenia Glukhov, Lena Gerwick,Chen Zhang, Thomas F. Murray, and William H. Gerwick*. Samholides, Swinholide-Related Metabolites from a Marine Cyanobacterium cf. Phormidium sp. Journal of Organic Chemistry, 2018, 83, 3034−3046.

  14. Mei-Jun Chu, Xu-Li Tang, Xiao Han, Tao Li, Xiang-Chao Luo, Ming-Ming Jiang, Leen van Ofwegen, Lian-Zhong Luo, Gang Zhang, Ping-Lin Li,* and Guo-Qiang Li*. Metabolites from the Paracel Islands Soft Coral Sinularia cf. molesta. Marine Drugs, 2018, 16, 517.

  15. Guo-Fei Qin, Xu-Li Tang, Yan-Ting Sun, Xiang-Chao Luo, Jing Zhang, Leen van Ofwegen, Ping-Jyun Sung, Ping-Lin Li* and Guo-Qiang Li*. Terpenoids from the Soft Coral Sinularia sp. Collected in Yongxing Island. Marine Drugs, 2018, 16, 127.

Books

 

 

 

 

《SymbioticMicrobiomes ofCoral Reefs Spongesand Corals》,Springer Nature B.V., 2019

Patents

 

 

 

 

 

Projects

1. 2019/01-2022/12, NSFC,41876161,Search for the Origin of Marine Cembrane Diterpenoids and Discovery of New Structural Activity Leading Compounds,Project leader

 

 









 

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