Feng Han


Feng Han, male, PhD, associate professor, master’s supervisor.


Contact information:

Add: 5 Yushan Road, Qingdao, 266003, China

Tel: 0532-82032067, Fax: 0532-82033054, E-mail: fhan@ouc.edu.cn


Educational background:

2003.9–2008.6: Ph. D. in Aquatic Products Processing and Storage Engineering at Ocean University of China.

1996.9–1999.6: M.S. in Microbiology at Shandong University.

1992.9–1996.6: B.Sc. in Microbial Engineering at Shandong University.


Employment History:

2013.1–: Associate professor in School of Medicine and Pharmacy, Ocean University of China, China.

2011.3–2012.3: Invited scholar in School of Medicine, University of North Carolina at Chapel Hill, USA.

2003.10–2012.12: Lecturer in School of Medicine and Pharmacy, Ocean University of China, China.

1999.7–2002.9: Assistant professor in Institute of Marine Drugs and Foods, Qingdao Ocean University, China.


Research field:

1. R&D of marine polysaccharides-degrading enzymes

2. R&D of novel antibiofilm drugs


Selected Publications:

(*corresponding author; #these authors contributed equally to this work.)


1. Su Ma, Gaofei Duan, Wengang Chai, Cunliang Geng, Yulong Tan, Lushan Wang, Frédéric Le Sourd, Gurvan Michel, Wengong Yu, Feng Han*. Purification, cloning, characterization and essential amino acid residues analysis of a new ι-carrageenase from Cellulophaga sp. QY3.PLoS One, 2013,8(5): e64666. (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0064666)


2. Su Ma, Yulong Tan, Wengong Yu, Feng Han*. Cloning, expression and characterization of a new ι-carrageenase from marine bacterium Cellulophaga sp.. Biotechnol Lett, 2013, 35(10): 1617-1622. (http://link.springer.com/article/10.1007%2Fs10529-013-1244-0)


3. Ya Wang, Enwen Guo, Wengong Yu, Feng Han*. Purification and characterization of a new alginate lyase from marine bacterium Vibrio sp.. Biotechnol Lett, 2013, 35(5): 703-708.(http://link.springer.com/article/10.1007%2Fs10529-012-1134-x)


4. Shangyong Li#, Panpan Jia#, Linna Wang, Wengong Yu, Feng Han*. Purification and characterization of a new thermostable κ-carrageenase from the marine bacterium Pseudoalteromonas sp. QY203. J Ocean Univ China, 2013, 12(1): 155-159.(http://www.cnki.com.cn/Article/CJFDTotal-QDHB201301022.htm)


5. Yulong Tan#, Feng Han#, Su Ma, Wengong Yu*. Carboxymethyl chitosan prevents formation of broad-spectrum biofilm. Carbohydr Polym, 2011, 84(4): 1365-1370. (http://www.sciencedirect.com/science/article/pii/S0144861711000695)


6. Peng Jiang, Jingbao Li, Feng Han, Gaofei Duan, Xinzhi Lu, Yuchao Gu, Wengong Yu*. Antibiofilm activity of an exopolysaccharide from marine bacterium Vibrio sp. QY101. PLoS One, 2011, 6(4): e18514. (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0018514)


7. Shuai Man, Rubin Cheng, Cuicui Miao, Qianhong Gong, Yuchao Gu, Xinzhi Lu, Feng Han, Wengong Yu*. Artificial trans-encoded small non-coding RNAs specifically silence the selected gene expression in bacteria. Nucleic Acids Res, 2011, 39(8): e50. (http://nar.oxfordjournals.org/content/39/8/e50.long)


8. Yuchao Gu, Wenyi Mi, Yuqing Ge, Haiyan Liu, Qiong Fan, Cuifang Han, Jing Yang, Feng Han, Xinzhi Lu, Wengong Yu*. GlcNAcylation plays an essential role in breast cancer metastasis. Cancer Res, 2010, 70(15): 6344-6351. (http://cancerres.aacrjournals.org/content/70/15/6344.long)


9. Gaofei Duan#, Feng Han#, Wengong Yu*. Cloning, sequence analysis and expression of gene alyPI encoding an alginate lyase from marine bacterium Pseudoalteromonas sp. CY24. Can J Microbiol, 2009, 55(9): 1113-1118. (http://www.ncbi.nlm.nih.gov/sites/pubmed/19898554)


10. Xinzhi Lu, Yan Chu, Qianqian Wu, Yuchao Gu, Feng Han, Wengong Yu*. Cloning, expression and characterization of a new agarase-encoding gene from marine Pseudoalteromonas sp.. Biotechnol Lett, 2009, 31(10): 1565-1570. (http://www.springerlink.com/content/uu45u866t80756x7)


11. Cuiping Ma, Xinzhi Lu, Chao Shi, Jingbao Li, Yuchao Gu, Yiming Ma, Yan Chu, Feng Han, Qianhong Gong, Wengong Yu*. Molecular cloning and characterization of a novel β-agarase, AgaB, from marine Pseudoalteromonas sp. CY24. J Biol Chem, 2007, 282(6): 3747-3754. (http://www.jbc.org/cgi/content/full/282/6/3747)


12. Jingbao Li, Feng Han, Xinzhi Lu, Xiaoyan Fu, Cuiping Ma, Yan Chu, Wengong Yu*. A simple method of preparing diverse neoagaro-oligosacharides with β-agarase. Carbohydr Res, 2007, 342(8): 1030-1033. (http://www.sciencedirect.com/science/article/pii/S0008621507000729)