Wengong Yu, male, MD, professor of molecular biology, PhD supervisor.
Contact information:
Add: 5 Yushan Road, Qingdao, 266003, China
Tel: 0532-82031680
E-mail: yuwg66@ouc.edu.cn
Educational background:
MD: Osaka University, Japan (1997)
B.S.Med: Shandong Medical University, China (1988)
Employment history:
1998.10-now: School of Medicine and Pharmacy, Ocean University of China, China
1997.4-1998.9: School of Medicine, Osaka University, Japan
1988.8-1990.3: Shandong Medical University Hospital, China
Awards and honors:
1. Topnotch talent of Qingdao, 2013.
2. First class award of State Technological Invention Award (3rd), 2009.
3. Second class of innovation award of State Oceanic Administration (2nd), 2003.,
Research interests:
1. Molecular enzymology, especially R&D of marine polysaccharide degrading enzymes.
2. Research on novel anti-infective agents using bacterial quorum sensing and biofilm as targets.
3. Molecular mechanism of glycosyltransferases and cancer metastasis.
Selected publications:
1． Su Ma, Gaofei Duan, Wengang Chai, Cunliang Geng, Yulong Tan, Lushan Wang, Frédéric Le Sourd, Gurvan Michel, Wengong Yu, Feng Han. Purification, cloning, characterization and essential amino acid residues analysis of a new ι-carrageenase from Cellulophaga sp. QY3. PLoS One, 2013; 8(5): e64666. (IF: 3.73) (http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0064666)
2． Shuai Man, Rubin Cheng, Cuicui Miao, Qianhong Gong, Yuchao Gu, Xinzhi Lu, Feng Han, andWengong Yu. Artificial trans-encoded small noncoding RNAs specifically silence the selected gene expression in bacteria. Nucleic Acids Res, 2011;39(8):e50. (IF:7.836)(http://nar.oxfordjournals.org/content/39/8/e50.long)
3． Yuchao Gu, Wenyi Mi, Yuqing Ge, Haiyan Liu, Qiong Fan, Cuifang Han, Jing Yang, Feng Han, Xinzhi Lu, andWengong Yu. GlcNAcylation Plays an Essential Role in Breast Cancer Metastasis. Cancer Res, 2010; 70(15):6344-51. (IF:8.234)(http://cancerres.aacrjournals.org/content/70/15/6344.long)
4． Wenyi Mi, Yuchao Gu, Cuifang Han, Haiyan Liu, Qiong Fan, Xinling Zhang, Qi Cong, andWengong Yu. O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy. BBA-MolecularBasis of Disease, 2011; 1812(4):514-9. (IF:5.211)(http://www.sciencedirect.com/science/article/pii/S0925443911000226)
5． Peng Jiang, Jingbao Li, Feng Han, Gaofei Duan, Xinzhi Lu, Yuchao Gu,Wengong Yu. Antibiofilm activity of an exopolysaccharide from marine bacterium Vibrio sp. QY101.PLoS One. 2011; 6(4):e18514. (IF:4.411)(http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0018514)
6． Yulong Tan, Feng Han, Su Ma,Wengong Yu. Carboxymethyl chitosan prevents formation of broad-spectrum biofilm.Carbohydr Polym.2011; 84(4): 1365-1370. (IF:3.167)(http://www.sciencedirect.com/science/article/pii/S0144861711000695)
7． Junli Ye, Yantao Han, Chunbong Wang,Wengong Yu.Cytoprotective effect of polypeptide from Chlamys farreri on neuroblastoma (SH-SY5Y) cells following HO exposure involves scavenging ROS and inhibition JNK phosphorylation.J Neurochem. 2009 ;111(2):441-51. (IF:4.337)(http://onlinelibrary.wiley.com/doi/10.1111/j.1471-4159.2009.06328.x/pdf
8． Yuchao Gu, Junhua Zhang, Wenyi Mi, Jing Yang, Feng Han, Xinzhi Lu,Wengong Yu. Silencing of GM3 synthase suppresses lung metastasis of murine breast cancer cells. Breast Cancer Res, 2008; 10(1): R1.(IF:5.785)(http://breast-cancer-research.com/content/10/1/R1
9． Cuiping Ma, Xinzhi Lu, Chao Shi, Jingbao Li, Yuchao Gu, Yiming Ma, Yan Chu, Feng Han, Qianhong Gong,Wengong Yu. Molecular cloning and characterization of a novel β-agarase, AgaB, from marinePseudoalteromonassp. CY24. J Biol Chem, 2007; 282(6): 3747-3754. (IF:5.328)(http://www.jbc.org/cgi/content/full/282/6/3747)
