Shi Wang

Name: Shi Wang

Title: Professor




College of Marine Life Sciences,

Ocean University of China,

5 Yushan Road, Qingdao, China

Lab  website:



1998~2002, Ocean University of China, B.S.;

2002~2007, Ocean University of China, Ph.D.;

Research &  Teaching

2007~2009, University of Texas at Austin, Integrative Biology, Postdoc;

2009~2010, University of Texas at Austin, Neurobiology, Postdoc;

2011~, Ocean University of China, College of Marine Life Sciences, Professor.

Research Interests

My research interests focus on scallop genetics, genomics and  breeding. I am particularly interested in understanding of genetic bases of  scallop growth, reproduction, stress-resistance and adaptive evolution.  During recent years, our group has generated a large amount of genetic and  genomic resources for scallops, and has also developed new varieties with superior  traits such as rapid growth and stress-resistance. Our recent work involves  with whole-genome sequencing of several scallop species of economic  significance, elucidation of key genes and their regulatory networks  underlying important traits, and development of genomic selection techniques  suitable for scallops. We have developed a series of high-throughput “-omics”  methods for genome-wide genotyping, gene expression and DNA methylation  profiling in non-model organisms. We are now in the process of developing an  integrated genomic approach to unravel the genetic bases of important traits,  which would not only deepen our understanding of the biology and evolution of  Pectinidae but also speed up the progress of genetic breeding aiming for  sustainable scallop aquaculture.

Publications (# cofirst author; *corresponding author)

Note,  for most recent publications, please visit:

1.Wang S#,*,  Meyer E#,*, McKay JK & Matz MV. (2012) 2b-RAD: a simple and flexible  method for genome-wide genotyping. Nature  Methods. 9: 808-810. (5-Yr IF: 23.2)

2.Jiao W#, Fu X#,  Dou J#, Li H, Su H, Mao J, Yu Q, Zhang L, Hu X, Huang X, Wang S* & Bao Z*.  (2013) High-resolution linkage and quantitative trait locus mapping aided by  genome survey sequencing: building up an integrative genomic framework for a  bivalve mollusc. DNA Research. (In  press, doi:10.1093/dnares/dst043) (5-Yr IF: 5.5)

3.Jiao W#, Fu X#,  Li J#, Li L, Feng L, Lv J, Zhang L, Wang X, Li Y, Hou R, Zhang L,  Hu X, Wang S* & Bao  Z*. (2013) Large-scale development of gene-associated SNP markers  for molluscan population genomic, comparative genomic and genome-wide  association studies. DNA Research.  (In press, doi:10.1093/dnares/dst048) (5-Yr IF: 5.5)

4.Fu X#, Dou J#,  Mao J, Su H, Jiao W, Zhang L, Hu X, Huang X, Wang S* & Bao Z*. (2013) RADtyping: an  integrated package for accurate de novo  codominant and dominant RAD genotyping in mapping populations. PLoS ONE. 8: e79960.  (5-Yr IF: 4.2)

5.Ponomarev I*,#, Wang S#, Zhang L, Harris  RA & Mayfield RD*. (2012) Gene co-expression networks in human  brain identify epigenetic modifications in alcohol dependence. Journal of Neuroscience. 32:  1884-1897. (5-Yr IF: 7.9)

6.Dou J, Zhao X, Fu X, Jiao W,  Wang N, Zhang L, Hu X, Wang S*  & Bao Z*. (2012) Reference-free SNP calling: Improved accuracy  by preventing incorrect calls from repetitive genomic regions. Biology Direct. 7: 17.  (5-Yr IF: 3.1)

7.Zhang L, Hou R, Su H, Hu X, Wang S* & Bao Z*.  (2012) Network analysis of oyster transcriptome revealed a cascade of  cellular responses during recovery after heat shock. PLoS ONE. 7: e35484. (5-Yr IF: 4.2)

8.Wang S,  Zhang L, Hu J, Bao Z* & Liu Z*. (2010) Molecular  and cellular evidence for biased mitotic gene conversion in hybrid scallop. BMC Evolutionary Biology. 10: 6.  (5-Yr IF: 4.4)

9.Wang S*, Zhang L, Meyer E & Matz MV. (2009) Construction of a  high-resolution genetic linkage map and comparative genome analysis for the  reef-building coral Acropora millepora.  Genome Biology. 10: R126.  (5-Yr IF: 9.0)

10.Wang S,  Zhang L, Zhan A., Wang X, Liu Z, Hu J & Bao Z*. (2007) Patterns  of concerted evolution of the rDNA family in a natural population of Zhikong  scallop, Chlamys farreri. Journal of Molecular Evolution. 65:  660-667. (5-Yr IF: 2.4)