Research Interests
Cellular processes and regulatory mechanisms of tubulogenesis;
Mechanisms of tissue elongation and retraction;
Biophysical basis of morphogenesis and organogenesis;
The origin of important organs, genomic basis of adaptation, and co-evolution of the host with its microorganisms.
Group Members
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Dr. DONG Bo 董波 Professor | Dr. YU Haiyan 于海燕 Associate Professor | Dr. YANG Xiuxia 杨秀霞 Associate Professor | Dr. LYU Zhiyi 吕志一 Associate Professor |
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Dr. WEI Jiankai 隗健凯 Lecturer | Dr. YANG Likun 杨立昆 Lecturer | ||
Projects
General Program of National Natural Science Foundation of China (NSFC): 4 projects
Youth Program of National Natural Science Foundation of China (NSFC): 2 projects
Key Project of Intergovernmental International Cooperation on Scientific and Technological Innovation: 1 project
Key Scientific and Technical Innovation Projects of Shandong Province: 2 projects
Representative Publications and Achievements
1. Lu Q#, Gao Y#, Fu Y, Peng H, Shi W, Li B, Lv Z, Feng X, Dong B*, Ciona embryonic tail bending is driven by asymmetrical notochord contractility and coordinated by epithelial proliferation. Development. 2020. 147. doi:10.1242/dev.185868. (Research highlight, IF=5.61)
2. Wei J, Zhang J, Lu Q, Ren P, Guo X, Wang J, Li X, Chang Y, Duan S, Wang S, Yu H, Zhang X, Yang X, Gao H, Dong B*, Genomic basis of environmental adaptation in the leathery sea squirt (Styela clava). Molecular Ecology Resources. 2020. https://doi.org/10.1111/1755-0998.13209. (Highlight paper, IF=6.28)
3. Bhattachan P, Rae J, Yu H, Jung W, Wei J, Parton R. G, and Dong B*, Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis. The FASEB Journal, 2020, 34 (1): 1345-1361. (IF=5.33)
4. Sehring I, Recho P, Denker E, Kourakis M, Mathiesen B, Hannezo E*, Dong B*, Jiang D*. 2015. Assembly and positioning of actomyosin rings by contractility and planar cell polarity. eLife 4: e09206. (Highlight，faculty of 1000 recommendation, IF=8.33)
5. Hannezo E#, *, Dong B#, *, Recho P, Joanny JF, Hayashi S. 2015. A cortical instability drives periodic supracellular actin pattern formation in epithelial tubes. PNAS 112 (28): 8620-8625. (IF=9.28)
6. Dong B, Hayashi S. Shaping of biological tubes by mechanical interaction of cell and extracellular matrix. Current Opinion in Genetics & Development, 2015, 32: 129-134. (IF=7.82)
7. Sehring I#, Dong B#, Denker E, Bhattachan P, Deng W, Mathiesen B, Jiang D. An equatorial contractile mechanism drives cell elongation but not cell division. PLoS Biology, 2014,12(2): e1001781. (faculty of 1000 recommendation. IF=10.21)
8. Dong B*, Hannezo E, Hayashi S*. 2014. Balance between apical membrane growth and luminal matrix resistance determines the shape of epithelial tubule. Cell Reports 7(4): 941-950. (IF=8.21)
9. Dong B, Miao GX, Hayashi S. A fat body-derived apical extracellular matrix enzyme is transported to the tracheal lumen and is required for tube morphogenesis in Drosophila. Development, 2014 141 (21): 4104-4109. (Highlight paper, IF=6.62)
10. Dong B, Kakihara K, Otani T, Wada H, Hayashi S. 2013. Rab9 and retromer regulate retrograde trafficking of luminal protein required for epithelial tube length control. Nature Communications 4, 1358. (IF=12.34)
