Lab of Biochemistry & Functional Materials

生物化学与功能材料研究室

Research Interests

Our group is mainly interested in the research field of marine biomaterials & living resources comprehensive utilization.

Marine biomaterials:

Functional materials based on biological macromolecules: extraction, screening, modifications and characterizations;

Design of a series of structure and morphology controllable functional materials: nanoparticles, nanomembranes, nanocapsules, nanotubes, nanofiber, microcapsules, microspheres and phase-change materials.

Biological activities investigation of marine biomaterials: anticoagulant, antibacterial activity, antifungal activity, moisture retention, hygroscopicity, promote healing, act.

Marine living resources complex utilization:

Bioactive constituents come from marine organisms and aquatic product processing offal: isolation, preparation, screening, modification and characterization;

Application of marine living resource in water purification, food preservation and heavy metal ions adsorption.


Group Members


WANG MinJIANG Yong


Dr. LIU Chengsheng  刘成圣

Professor

Dr. DANG Qifeng  党奇峰

Associate Professor


Projects

1. Preparation of dual-release multifunctional in situ formed composite hydrogel dressing and its wound repair mechanism. The National Natural Science Foundation of China.

2. Promote wound hemostasis and healing mechanism of hydrogel/nanoparticle composite drug delivery. Shandong Provincial Natural Science Foundation.

3. Preparation of chitosan-based composite hydrogel and its effective application on wound tissue repair. Projects of International Cooperation and Exchanges.

4. Preparation and antibacterial mechanism of solid-phase nano-antibacterial system root in natural marine polysaccharide. Shandong Provincial Natural Science Foundation.

5. Design of thermosensitive hydrogels as a 3D culture system for marine biological cell. The National Natural Science Foundation of China.


Representative Publications and Achievements

1.Haifeng Zhang, Qifeng Dang, Chengsheng Liu, Dejun Yu, Yan Wang, Xiaoying Pu, Yan Liu, Yuanyuan Liang, Dongsu Cha. Fabrication of methyl acrylate and tetraethylenepentamine grafted magnetic chitosan microparticles for capture of Cd(II) from aqueous solutions. Journal of Hazardous Materials 366 (2019) 346–357.

2.Yan Wang, Qifeng Dang, Chengsheng Liu, Dejun Yu, Xiaoying Pu, Qiongqiong Wang, Hong Gao, Bainian Zhang, and Dongsu Cha. Selective Adsorption toward Hg(II) and Inhibitory Effect on Bacterial Growth Occurring on Thiosemicarbazide-Functionalized Chitosan Microsphere Surface. ACS Applied Materials & Interfaces, 2018, 10: 40302-40316

3.Haifeng Zhang, Qifeng Dang, Chengsheng Liu*, Dongsu Cha, Zhenzhen Yu, Wenjing Zhu,and Bing Fan. Uptake of Pb(II) and Cd(II) on chitosan microsphere surface successively grafted by methyl acrylate and diethylenetriamine. ACS Applied Materials & Interfaces,2017,9: 11144-11155.

4.Shengnan Liang1, Qifeng Dang1, Chengsheng Liu, Yubei Zhang, Yan Wang, Wenjing Zhu, Guozhu Chang, Hantian, Sun, Dongsu, Cha, Bing Fan. Characterization and antibacterial mechanism of poly(aminoethyl) modified chitin synthesized via a facile one-step pathway Carbohydrate Polymers 195 (2018) 275–287

5.Zhenzhen Yu1, Qifeng Dang1, Chengsheng Liu, Dongsu Cha, Haifeng Zhang, Wenjing Zhu, Qianqian Zhang, Bing Fan. Preparation and characterization of poly(maleic acid)-graftedcross-linked chitosan microspheres for Cd(II) adsorption. Carbohydrate Polymers, 2017, 172: 28–39.

6.Yanyan Yin1, Qifeng Dang1, Chengsheng Liu, Jingquan Yan, Dongsu Cha, Zhenzhen Yu, Yachan Cao, Yan Wang, Bing Fan. Itaconic acid grafted carboxymethyl chitosan and its nanoparticles:Preparation, characterization and evaluation. International Journal of Biological Macromolecules, 2017, 102: 10–18.

7.Qifeng Dang, Qianqian Zhang, Chengsheng Liu, Jingquan Yan, Guozhu Chang, Ying Xin, Xiaoyu Cheng, Yachan Cao, Hong Gao, Yan Liu.Decanoic acid functionalized chitosan: Synthesis, characterization, and evaluation as potential wound dressing material. International Journal of Biological Macromolecules 139 (2019) 1046–1053

8.Qifeng Dang1, Kai Liu1, Chengsheng Liu, Tao Xu, Jingquan Yan, Feilong Yan, Dongsu Cha, Qianqian Zhang, Yachan Cao. Preparation, characterization, and evaluation of 3,6-O-Nacetylethylenediamine modified chitosan as potential antimicrobial wound dressing material. Carbohydrate Polymer. 2018, 180: 1-12.

9.Qifeng Dang1, Kai Liu1, Zhenzhen Zhang, Chengsheng Liu, Xi Liu, Ying Xin, Xiaoyu Cheng, Tao Xu, Dongsu Cha, Bing Fan. Fabrication and evaluation of thermosensitive chitosan/collagen/α,β-glycerophosphate hydrogels for tissue regeneration. Carbohydrate Polymers, 2017, 167: 145–157.

10.Yubei Zhang1, Qifeng Dang1, Chengsheng Liu, Jingquan Yan, Dongsu Cha, Shengnan Liang, Xiaoli Li, Bing Fan. Synthesis, characterization, and evaluation of poly(aminoethyl)modified chitosan and its hydrogel used as antibacterial wounddressing. International Journal of Biological Macromolecules, 2017, 102: 457–467.