LIU Guanglei 刘光磊

Lab of Metabolic Engineering of Marine Microorganisms


LIU Guanglei  刘光磊

Professor

Ph.D. Microbiology

  

Tel: 

Email: liugl@ouc.edu.cn

Add.: Ocean University of China, Yushan Campus, Science Building,5 Yushan Road, 266003, Qingdao, P.R.C.

  

Research Interests

My research mainly focusses on polysaccharide hydrolase, bioresources, metabolic pathways, genetic regulation of marine microorganisms

  

Academic Qualifications

2004-2008: B.Sc. Biology, Ocean University of China

2008-2012: Ph.D. Microbiology , Ocean University of China

  

Working Experience

2021-current: Associate Professor, College of Marine Life Sciences, Ocean University of China

2014-2020: Associate Professor, College of Marine Life Sciences, Ocean University of China

2013-2014: Lecturer, College of Marine Life Sciences, Ocean University of China

2012-2013: Assistant researcher, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences

  

Representative Publications

1)Wei, X. #, Liu, G. L. #, Jia, S. L., Chi, Z., Hu, Z., & Chi, Z. M. Pullulan biosynthesis and its regulation in Aureobasidium spp. Carbohydrate Polymers, 2020, 117076.

2)Liu G#, Zhao X#, Chen C, Chi Z, Zhang Y, Cui Q, Chi Z, Liu YJ. Robust production of pigment-free pullulan from lignocellulosic hydrolysate by a new fungus co-utilizing glucose and xylose. Carbohydrate Polymers. 2020 Aug 1;241:116400

3)Chen, T. J. #, Liu, G. L. #, Chen, L., Yang, G., Hu, Z., Chi, Z. M., & Chi, Z. Alternative primers are required for pullulan biosynthesis in Aureobasidium melanogenum P16. International journal of biological macromolecules, 2020, 147, 10-17

4)Xue SJ#, Liu GL#, Chi Z#, Gao ZC, Hu Z, Chi ZM. Genetic evidences for the core biosynthesis pathway, regulation, transport and secretion of liamocins in yeast-like fungal cells. Biochemical Journal. 2020 Mar 13;477(5):887-903.

5)Mao, W. #, Han, Y. #, Wang, X., Zhao, X., Chi, Z., Chi, Z.M., & Liu, G. * A new engineered endo-inulinase with improved activity and thermostability: Application in the production of prebiotic fructo-oligosaccharides from inulin. Food chemistry,2019, 294, 293-301.

6)Wang, M. #, Mao, W. #, Wang, X., Li, F., Wang, J., Chi, Z., Chi, Z. M. & Liu, G. * Efficient simultaneous production of extracellular polyol esters of fatty acids and intracellular lipids from inulin by a deep-sea yeast Rhodotorula paludigena P4R5. Microbial cell factories, 2019, 18(1), 149.

7)Han YZ, Zhou CC., Xu, YY., Yao JX., Chi, Z, Chi ZM., & Liu GL*. High-efficient production of fructo-oligosaccharides from inulin by a two-stage bioprocess using an engineered Yarrowia lipolytica strain. Carbohydrate Polymers, 2017, 173, 592.

8)Zhou SH, Liu Y, Zhao YJ, Chi Z, Chi ZM, Liu GL*. Enhanced exo-inulinase activity and stability by fusion of an inulin-binding module. Applied microbiology and biotechnology, 2016, 100(18): 8063–8074

9)Liu GL, Chi Z, Wang GY, Wang ZP, Li Y, Chi ZM*. Yeast killer toxins, molecular mechanisms of their action and their applications. Crit Rev Biotechnol. 2015, 352222-234

10)Liu GL#, Chi Z#, Chi ZM*. Molecular characterization and expression of microbial inulinase genes. Critical reviews in microbiology. 2013. 39(2):152-165

  

Awards

1. Metabolisms and regulation of renewable biofuels of yeasts, The 2nd prize of Provincial Award for Science and Technology, 2020.

2. Biosynthesis and regulation of yeast inulinases, The third prize of Municipal Award for Science and Technology, 2012.