Wen haishen
Professor, Laboratory of Fish Physiology and reproduction
Department of Aquaculture, Fisheries College, Ocean University of China
5 Yushan Road, Phone: 86-532-82031825
Qingdao 266003, Fax: 86-532-82031176
P. R. China Email:wenhaishen@ouc.edu.cn
EDUCATION
u BS, B.S. Zootechnical Science, Department of Animal Science, Inner Mongolia Nationality University, Tongliao, Inner Mongolia Autonomous Region, PRC.1987
u MS, Hydrobiology, Fisheries College, Central China Agricultural University, Wuhan, Hubei province, PRC.1997
u PhD, Hydrobiology, School of Life Science, Sun Yat-sen University, Guangzhou, Guangdong province, PRC. 2001
RESEARCH
Research Interests:
My research interest focuses on reproduction and endocrinology physiology of the finfish, especially the basic and application of hormonal manipulation spawning in aquaculture catfish, flounder and marine fishes.
Current Research Projects (recent 10 years):
u Regulation mechanism of reproductive endocrine function in viviparity Sebastes schlegeli(Z2008D03), key fund of Shandong province, 2008.12 -2011.12.
u The industrialization of farming research and demonstration of cold water fishes (201003055), Special Fund for Agroscientific Research in the Public Interest, 2010.1- 2014.12.
u Breeding technique of Trachidermus fasciatus in a large scale, scientific and technological project of Shandong province (2010GHY10517), 2010.1- 2012.12.
u The research and development technology in Seawater pond cleaning (2011BAD13B03)”, National Key Technology R&D Program in the 12th Five year Plan of china,2011.1-2015.12.
u Effects of offshore hypoxia on reproduction performance in Sebastes schlegeli and its molecular endocrine mechanism, Natural Science Funds (41176122), 2012.1-2015.12.
u The heredity and breeding based on whole genome in (Cynoglossus semilaevis), High- Technology Development Program in the 12th Five year Plan of China. (2011AA10A403), 2002.1-2005.12.
Honors:
u 09/2001-present, Senior member in China Society of Fisheries, Committee Member of Freshwater Fisheries in China Society of Fisheries.
u 09/2007-present, Committee Member of Fisheries Biotechnology in China Society of Fisheries.
u 09/2005-present, Reviewer for The National Science Funds.
u 09/2010-present, Reviewer for research projects of Guangdong Province, Shandong Province and Qingdao City.
u 01/2011-present, Committee Member for Industry Strategy Alliance of Cold Water Fishes in China.
u 07/2008- present, Expert of Education and Teaching research in Ocean University of China.
u 09/2003- present, Vice director of “National Base of Life Science and Technology Personnel Education” .
u 09/2008- present, Vice president, College of Fisheries, Ocean University of China.
u 01/2011- present, Director, Teaching Experimental Center of Fisheries Science, State-level Experimental Teaching Demonstration Center.
PUBLICATION (recent 10 years)
u Wen Hai S, Hao R. Lin,Yu Z. Mao, Liang Wang & Ya P. Zhanga. Annual variations of gonadotropin content and ovarian development of feral female catfish, Silurus asotus, in central China.Environmental Biology of Fishes, 2003,68:283-291.
u Wen H S,H R Lin. Effects of exogenous neurohormone, gonadotropin (GtH) and dopaminergic drugs on the serum GtH content and ovulatory responsiveness of wild catfish, Silurus asotus (Linnaeus,1758). Aquaculture Research, 2004,35:204- 212.
u He Feng, Hai S. Wen*, Shuang L. Dong, Bao Shi, Cai F. Chen, Lian S. Wang, Jun Yao, Xing J. Mu, Yu G. Zhou. Identification of single nucleotide polymorphism cytochrome P450-c19a and its relation to reproductive traits in Japanese flounder (Paralichthys olivaceus).Aquaculture, 2008, 279:177-181.
u He Feng, Hai Shen Wen*, Shuang Lin Dong, Lian Shun Wang, Cai Fang Chen, Bao Shi, Xing Jiang Mu, Jun Yao, Yu Guo Zhou. Identification of estrogen receptor α gene polymorphisms by SSCP and its effect on reproductive traits in Japanese flounder (Paralichthys olivaceus).Comparative Physiology and Biochemistry Part B. 2008, 150: 278- 283.
u He Feng, Hai Shen Wen*, Shuang Lin Dong, Bao Shi, Cai Fang Chen , Lian Shun Wang, Jun Yao, Xing Jiang Mu, Yu Guo Zhou. Polymorphisms within promoter of Japanese flounder(Paralichthys olivaceus) ovary cytochrome P450-c19(CYP19a) gene associated with reproductive traits.Fish Physiology and Biochemistry. 2009,35:333-340.
u Shi Bao, Hai Shen Wen*, Feng He, Shuang Lin Dong, Shen Ma, Cai Fang Chen, Xiao Yan Chen, Jia Ren, Zhang, Guo Xiong Jin. Single nucleotide polymorphisms within the estrogen receptor beta gene are linked with reproductive indices in Japanese flounder, Paralichthys olivaceus.Comparative Physiology and Biochemistry Part B, 2009, 154:62-67.
u Shi Bao, Hai S. Wen*, Feng He, Shuang L. Dong, Shen Ma, Cai F. Chen, Lian S. Wang, Jun Yao, Xing J. Mu, Yu G. Zhou. Association of reproductive performance with SNPs of FOXL2 gene by SSCP in Japanese flounder (Paralichthys olivaceus).Comparative Physiology and Biochemistry Part B, 2009, 153:1-7.
u Chen Cai F, Hai S. Wen*, Zhao P. Wang, Feng He, Jia R. Zhang, Xiao Y. Chen, Guo X. Jin, Bao Shi, Dan Shi, Yan P. Yang, Ji F. Li, Bao X. Qi, Na Li. Cloning and expression of P450c17-I (17a- hydroxylase/ 17,20-lyase) in brain and ovary during gonad development in Cynoglossus semilaevis.Fish Physiology and Biochemistry. 2010,36:1001-1012.
u Shi Dan, Hai S. Wen*, Feng He,JiF.Li, Yan P. Yang , Cai F. Chen, Jia R. Zhang, Xiao Y. Chen,Guo X. Jin, Bao Shi, Bao X. Qi,NaLi.The physiology functions of estrogen receptor a (ERa) in reproduction cycle of ovoviviparous black rockfish, Sebastes schlegeli Hilgendorf.Steriod,2011, 76: 1597-1608.
u LIU Miao, WEN Haishen*, HE Feng, LI Jifang, SHI Dan, HU Jian, ZHANG Yuanqing, MA Ruiqin, MU Weijie, and QI Baoxia. Expression Patterns of Cytochrome P450 Aromatase Genes During Ovary Development and Their Responses to Temperature Stress in Female Yellow Catfish (Pelteobagrus fulvidraco).J. Ocean Univ. China .2011, 10(4): 409-416.
u Jin Guo X, Hai S. Wen,* Feng He, Ji F. Li, Cai F. Chen, Jia R. Zhang, Xiao Y. Chen, Bao Shi, Dan Shi, Yan P. Yang, Bao X. Qi, Na Li. Molecular cloning, characterization expression of P450c17-I and P450c17-II and their functions analysis during the reproductive cycle in males of barfin flounder (Verasper moseri).Fish Physiology and Biochemistry. 2012,38:807–817.
u Ding YuXia1, Feng He*, Hai Shen Wen1, JiFang Li, Kun Qian, MeiLi Chi, Meng Ni,XiangHan Yin, Yan Bu, YiJie Zhao, DongQian Zhang. Polymorphism in exons CpG rich regions of the cyp17-II gene affecting its mRNA expression and reproductive endocrine levels in female Japanese flounder (Paralichthys olivaceus).General and Comparative Endocrinology, 2012,179:107-114.
u Chen Cai-Fang, Hai-Shen Wen*, Feng He, Ji-Fang Li & Bao-Xia Qi. Molecular mechanism of P450c17-II (17, 20-lyase) regulating gonad development in female Cynoglossus semilaevis.Aquaculture Research. 2013,44:1459-1469.
u Li Wenge ,Jiaren Zhang,Weijie Mu,Haishen Wen*. Cloning, characterization and expression of estrogen receptor beta in the male half-smooth tongue sole, Cynoglossus semilaevis.Fish Physiology and Biochemistry, DOI: 10.1007/s10695-012-9729-7.
u MU Weijie, WEN Haishen*, HE Feng, LI Jifang, LIU Miao, MA Ruiqin, ZHANG Yuanqing, HU Jian, and QI Baoxia.Cloning and Expression Analysis of vasa During the Reproductive Cycle of Korean Rockfish, Sebastes schlegeli.Journal Ocean University of China, 2013,12(1):115-124.DOI 10.1007 /s11802- 013- 1941-2.
u Mu W.J., H.S. Wen*, F.He, J.F. Li, M. Liu, R.Q. Ma, Y.Q. Zhang,J.Hu, B.X. Qi.Cloning and expression analysis of the cytochrome P450c17s enzymes during the reproductive cycle in ovoviviparous Korean rockfish (Sebastes schlegeli).Gene, 2013, 512:444–449.
u Mu Wei J., Hai S. Wen*, Feng He, Ji F. Li, Miao Liu,Yuan Q. Zhang,Jian Hu,Bao X. Qi.Cloning and expression analysis of follicle-stimulating hormone and luteinizing hormone receptor during the reproductive cycle in Korean rockfish (Sebastes schlegeli)Fish Physiology and Biochemistry, 2013, 39: 287–298.
u Wen Hai S.,Mu W J, Yang Yan P., Feng He, Ji F. Li, Dan Shi,Cai F. Chen, Jia R. Zhang, Xiao Y. Chen, Guo X. Jin, Bao Shi, Bao X. Qi. Molecular physiology mechanism of cytochrome P450 aromatase regulating gonad development in ovoviviparous black rockfish (Sebastes schlegeli). Aquaculture Research,doi:10.1111/are.12114.
u Mu W. J, H. S. Wen *, Ji F. Li, Feng He.Cloning and expression analysis of Foxl2 during the reproductive cycle in Korean rockfish, Sebastes schlegeli.Fish Physiology and Biochemistry, 2013,39:1419–1430.
u Mu Weijie,WenHai S.,*Shi Dan,Yang Yangping. Molecular cloning, characterization and expression analysis of estrogen receptor βs (ERβ1 and ERβ2) during gonad development in the Korean rockfish, Sebastes schlegeli. Gene, 2013,523:39-49.
u Ding YuXia, Feng He*, HaiShen Wen, JiFang Li, Meng Ni, MeiLi Chi, Kun Qian, Yan Bu, DongQian Zhang, YuFeng Si, JunLi Zhao. DNA methylation status of cyp17-Ⅱgene correlated with its expression pattern and reproductive endocrinology during ovarian development stages of Japanese flounder (Paralichthys olivaceus).Gene, 2013,527:82-88 .
u Mu Weijie , Haishen Wen*, Jifang Li, Feng He. Cloning and expression analysis of a HSP70 gene from Korean rockfish (Sebastes schlegeli).Fish & Shellfish Immunology. 2013,35:1111-1121.
