Qinghui Ai
Professor, Laboratory of Aquaculture Nutrition
Department of Aquaculture, Fisheries College, Ocean University of China
5 Yushan Road, Phone: 86-532-82031943
Qingdao 266003, Fax: 86-532-82031943
P. R. China Email:qhai@ouc.edu.cn
EDUCATION
MS, Aquaculture Nutrition, Shanghai Fisheries University, 1998
PhD, Institute of Hydrobiology, the Chinese Academy of Sciences, 2001
Postdoctoral, Ocean University of China, 2003
RESEARCH
Research Interest:
My research focuses on lipid and fatty acid metabolism as well as fish larval nutrition.
Specific Research Directions:
1. Lipid and fatty acid metabolism
We have concentrated our efforts on elucidating mechanisms of abnormal lipid metabolism syndrome caused by imbalanced nutrition from the aspects of fatty acid synthesis, oxidation, transportation and upload to specific tissues in marine fish species, like large yellow croaker, sea bass, turbot and grouper. We are also fascinated in the tight relationship between lipid metabolites (such as eicosanoid derived from LC-PUFA) and fish immunity, and mechanisms involved. Especially, traditionally accepted nonessential fatty acids (alfa linolenic acid (ALA) and linoleic acid (LA)) have been found to be critical in regulating marine fish physiology. Furthermore, to guarantee LC-PUFA concentration in the fillets of marine fish with low intake of marine derived resources (mainly fish meal and oil), LC-PUFA biosynthesis pathway and regulating mechanisms involved are being paid great attention to based on cell and heterologous yeast expression models. It was aimed to achieve the goal of fast growth, sound health and high fillet quality after large proportion of marine derived resources were replaced from diet formulation of marine fish.
2. Fish larval nutrition
We have studied larval fish nutrition for more than 10 years, which ranged from developmental process, feeding behavior, digestion physiology and nutritional requirement related with molecular mechanisms during these processes. On one hand, we are focusing on comparing nutritional metabolism among different fish species and different developmental phases to elucidate mechanisms during this special phase. On the other hand, we are trying to make feeds for larval fish by balancing nutrients, enhancing palatability and improving processing techniques to guarantee normal feed intake, growth performance and development process, as well as high survival and anti-stress capacity.
Current Research Projects (recent 10 years):
§ Project Title, Types of project funds (Grant No.),Beginning and ending years. For example:
§ Lipid deposition and its regulation mechanism in large yellow croaker, National Natural Science Foundation of China (Grant No. 31372541), 2014/01-2017/12,Total direct support-¥760,000. In progress, PI
§ Study on phospholipids metabolism of large yellow croaker larvae, National Natural Science Foundation of China (Grant No. 31172425), 2012/01-2015/12, Total direct support-¥560,000. In progress, PI
§ Comparative study of protein, polypeptide and amino acid metabolism of large yellow croaker larvae, Natural Science Foundation of China (Grant No. 31072222), 2011/01-2013/12, Total direct support- ¥330,000.In progress, PI
§ Effects of fatty acids on nutrition physiology and immunity of large yellow croaker, National Natural Science Foundation of China (Grant No. 30871930), 2009/01-2011/12, Total direct support-¥300,000. Concluded, PI
§ Effects of fatty acids on nutrition physiology and immunity of Japanese seabass, Ministry of Education, P.R. China,Program for New Century Excellent Talents (Grant No. NCET-07-0776), 2008/01-2010/12, Total direct support-¥500,000. Concluded, PI
§ Study on nutrition physiology of large yellow croaker larvae, National Natural Science Foundation of China (Grant No. 30400335), 2005/01 - 2007/12, Total direct support-¥210,000. Concluded, PI
§ Study on fatty acid metabolism and regulatory mechanism in large yellowcroaker， Ministry of Education of China, Doctoral Fund (Grant No. 20120132110007), 2013/01-2015/12, Total direct support-¥120,000, In progress, PI
§ Nutrition physiology study and micro-feed development technology of seawater larvae, National Technology Research andDevelopment Program (State 863 Program)(Grant No. 2004AA603610), 2004/03-2005/10, Total direct support-¥1,200,000. Concluded, PI
§ Finfish nutrition and feed post, National Flatfish Industrial Technology System (Grant No. CARS-50-G08), 2011/01- 2015/12, Total direct support-¥3,500,000. In progress.
§ Study of the key technology of healthy fingerlings propagation of new cultivation objects, National Science-Technology Support Program (Grant No. 2011BAD13B01), 2011/01-2015/12, Total direct support-¥860,000. In progress.
§ Nutrition requirements and the development of high efficiency formulated feed of aquatic animals, Ministry of Agriculture, P.R. China, Public Welfare Industry (agriculture) (Grant No. 201003020), 2010/01-2014/12, Total direct support-¥8,600,000. In progress.
§ Efficient environmental-friendly fishery feed preparation technology development and industrialization demonstration, the National “Eleventh Five-Year” plan ofScience and Technology support program (Grant No. 2006BAD03B03), 2006/01-2008/12, Total direct support-¥2,900,000.Concluded.
§ New technology development of large-scale breeding of large yellow croaker, National Technology Research andDevelopment Program (State 863 Program)(Grant No. 2004AA623010), 2004/03-2005/10, Total direct support-¥400,000.Concluded.
§ Research and development of efficient pollution-free feed of main representative fish, the National “Tenth Five-Year” science and technology research plan (Grant No. 2004BA526B-06), 2003/01-2005/12, Total direct support-¥1,200,000.Concluded.
Honors:
§ Senior Fellow, China Society of Fisheries
§ Senior Fellow, Chinese Society of Biotechnology(CSBT)
§ Academic Committee Expert of the key laboratory “Freshwater ecology and health” , Chinese Academy of Fishery Sciences
§ Evaluation expert, Natural Sciences Fund of Zhejiang Province
§ Evaluation expert, the Key Science-Technology Project of Fujian Province
§ Editorial Board Fellow , Aquaculture
§ Reviewer, Plos One, Fish and Shellfish Immunology, Aquaculture, Lipids, Aquaculture Nutrition, Aquaculture Research
PUBLICATION (recent 10 years)
Ai, Q. H., Xu, H.G., Mai, K.S., Xu, W., Wang, J., Zhang, W.B., 2011. Effects of dietary supplementation of Bacillus subtilis and fructooligosaccharide on growth performance, survival, non-specific immune response and disease resistance of juvenile large yellow croaker, Larimichthys crocea. Aquaculture 14(6), 515-522.
Ai, Q.H., Zhao, J.Z., Mai, K.S., Xu, W., Tan, B.P., Ma, H.M., Liufu, Z.G., 2008. Optimal dietary lipid level for large yellow croaker (Pseudosciaena crocea) larvae. Aquaculture Nutrition 14(6), 515-522.
Ai, Q.H., Mai, K.S., Zhang, W.B., Xu, W., Tan, B.P., Zhang, C.X., Li, H.T., 2007. Effects of exogenous enzymes (phytase, non-starch polysaccharide enzyme) in diets on growth, feed utilization, nitrogen and phosphorus excretion of Japanese seabass, Lateolabrax japonicus. Comparative Biochemistry and Physiology A 147, 502-508.
Ai, Q.H., Mai, K.S., Zhang, L., Tan, B.P., Zhang, W.B., Xu, W., Li, H.T., 2007. Effects of dietary ß-1, 3 glucan on innate immune response of large yellow croaker, Pseudosciaena crocea. Fish and Shellfish Immunology 22, 394-402.
Ai, Q.H., Mai, K.S., Huitao Li, Chunxiao Zhang, Lu Zhang, Duan Q.Y., Tan B.P., Xu W., Ma H.M., Zhang W.B., Liufu Z.G., 2004. Effects of dietary protein to energy ratios on growth and body composition of juvenile Japanese seabass, Lateolabrax japonicus. Aquaculture 230, 1-4.
Ai, Q.H.,Xie X.L., 2005. Effects of dietary soybean protein levels on energy budget of the southern catfish, Silurus meridionalis. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 4(141), 461-469.
Ai, Q.H., Mai, K.S., Zhang C.X., Xu W., Duan Q.Y., Tan B.P., Liufu Z.G.,2004. Effects of dietary vitamin C on growth and immune response of Japanese seabass, Lateolabrax japonicus. Aquaculture 242, 489-500.
Ai, Q.H., Mai, K.S., Tan B.P., Xu W., Zhang W.B., Ma H.M., Liufu Z.G., 2006. Effects of dietary vitamin C on survival, growth, and immunity of large yellow croaker, Pseudosciaena crocea. Aquaculture 261, 327-336.
Ai, Q.H., Mai, K.S., Tan B.P., Xu W., Duan Q.Y., Ma H.M., Zhang L., 2006. Replacement of fish meal by meat and bone meal in diets for large yellow croaker, Pseudosciaena crocea. Aquaculture 260, 255-263.
Xu H.G., Ai, Q.H., Mai, K.S., Xu W., Wang J., Zuo R.T., 2013. Effects of dietary supplementation of glycyrrhizic acid on growth performance, survival, innate immune response and parasite resistance in juvenile large yellow croaker, Larimichthys crocea (Richardson). Aquaculture Research, 1–9. (通讯作者)
Zhao J.Z., Ai, Q.H., Mai, K.S., Zuo R.T., Luo Y.W., 2013. Effects of dietary phospholipids on survival, growth, digestive enzymes and stress resistance of large yellow croaker, Larmichthys crocea larvae. Aquaculture 410, 122–128. (通讯作者)
Li Q.F., Ai, Q.H., Mai, K.S., Xu W., Zheng Y.F., 2013. A comparative study: in vitro effects of EPA and DHA on immune functions of head-kidney macrophages isolated from large yellow croaker (Larmichthys crocea). Fish and shellfish immunology35, 933-940. (通讯作者)
Zuo R.T., Ai, Q.H., Mai, K.S., Xu W., 2013. Effects of conjugated linoleic acid on growth, non-specific immunity, antioxidant capacity, lipid deposition and related gene expression in juvenile large yellow croaker (Larmichthys crocea) fed soyabean oil-based diets. British Journal of Nutrition 110, 1220-1232. (通讯作者)
Li W.J., Ai, Q.H., Mai, K.S., Xu W., Luo Y.W., Zhang Y.J., 2013. Effects of dietary amino acid patterns on growth and protein metabolism of large yellow croaker (Larimichthys crocea) larvae. Aquaculture 406, 1–8. (通讯作者)
Zuo, R.T., Ai, Q.H., Mai, K.S., Xu, W., Wang, J., Xu, H.G., Liufu, Z.G., Zhang, Y.J., 2012. Effects of dietary n-3 highly unsaturated fatty acids on growth, nonspecificimmunity, expression of some immune related genes and disease resistance oflarge yellow croaker (Larmichthys crocea) following natural infestation of parasites(Cryptocaryon irritans). Fish and Shellfish Immunology 32, 249-258. (通讯作者)
Zuo, R.T., Ai, Q.H., Mai, K.S., Xu, W., Wang, J., Xu, H.G., Liufu, Z.G., Zhang, Y.J., 2012. Effects of dietary docosahexaenoic to eicosapentaenoic acid ratio (DHA/EPA)ongrowth, nonspecific immunity, expression of some immune related genes anddisease resistance of large yellow croaker (Larmichthys crocea) following naturalinfestation of parasites (Cryptocaryon irritans). Aquaculture 334-337, 101-109. (通讯作者)
Li, Q.F., Ai, Q.H., Mai, K.S., Xu, W., Zheng, Y.F., 2012. In vitro effects of arachidonic acid on immune functions of head kidney macrophages isolated from large yellow croaker (Larmichthys crocea). Aquaculture330-333, 47-53. (通讯作者)
Yun, B., Ai, Q.H., Mai, K.S., Xu, W., Qi, G.S., Luo, Y.W., 2012. Synergistic effects of dietary cholesterol and taurine on growth performance and cholesterol metabolism in juvenile turbot (Scophthalmus maximus L.) fed high plant protein diets. Aquaculture, 324-325, 85-91. (通讯作者)
Chen,W., Ai, Q.H., Mai, K.S., Xu, W., Liufu, Z.G, Zhang, W.B., Cai, Y.H., 2011. Effects of dietary soybean saponins on feed intake, growth performance, digestibility and intestinal structure in juvenile Japanese flounder (Paralichthys olivaceus). Aquaculture 318, 95-100. (通讯作者)
Xue, J.P., Ai, Q.H., Mai, K.S., Xu, W., Yang, Y.H., Liufu, Z.G., 2011. Effects of melamine on growth performance and skin color of darkbarbel catfish (Pelteobagrus vachelli). Aquaculture 320, 142-146. (通讯作者)
Xie, F.J., Ai, Q.H., Mai, K.S., Xu, W., Ma, H.M., 2011. The optimal feeding frequency of large yellow croaker (Pseudosciaena crocea, Richardson) larvae. Aquaculture 311, 162-167. (通讯作者)
Wang, J., Ai, Q.H., Mai, K.S., Xu, W., Xu, H.G., Zhang, W.B., Wang, X.J., Liufu, Z.G., 2010. Effects of dietary ethoxyquin on growth performance and body composition of large yellow croaker, Pseudosciaena crocea. Aquaculture 36, 80-84. (通讯作者)
Xu, H.G., Ai, Q.H., Mai, K.S., Xu, W., Wang, J., Ma, H.M., Zhang, W.B., Wang, X.J., Liufu, Z.G., 2010. Effects of dietary arachidonic acid on growth performance, survival, immune response and tissue fatty acid composition of juvenile Japanese seabass, Lateolabrax japonicas. Aquaculture 307, 75-82. (通讯作者)
Cheng, Z.Y., Ai, Q.H., Mai, K.S., Xu, W., Ma, H.M., Li, Y., Zhang, J.M., 2010. Effects of dietary canola meal on growth performance, digestion and metabolism of Japanese seabass, Lateolabrax japonicus. Aquaculture 305, 102-108. (通讯作者)
Li, Y., Ai, Q.H., Mai, K.S., Xu, W., Cheng, Z.Y., 2012. Effects of the partial substitution of dietary fish meal by two types of soybean meals on the growth performance of juvenile Japanese seabass, Lateolabrax japonicus (Cuvier 1828). Aquaculture Research 43, 458-466. (通讯作者)
Yu, H.R., Ai, Q.H., Mai, K.S., Ma, H.M., Cahu, C.L., Infante, J.L.Z., 2012. Effects of dietary protein levels on the growth, survival, amylase and trypsin activities in large yellow croaker, Pseudosciaena Crocea R., larvae. Aquaculture Research43,178-186. (通讯作者)
Ren, M.C., Ai, Q.H., Mai, K.S., Ma, H.M., Wang, X.J., 2011. Effect of dietary carbohydrate level on growth performance, body composition, apparent digestibility coefficient and digestive enzyme activities of juvenile cobia, Rachycentron canadum L. Aquaculture Research42, 1467-1475. (通讯作者)
Li, Y., Ai, Q.H., Mai, K.S., Xu, W., Cheng, Z.Y., et al., 2010. Dietary leucine requirement for juvenile large yellow croaker Pseudosciaena crocea (Richardson, 1846). Journal of Ocean University of China (English Edition)9, 371-375. (通讯作者)
Zou, Y.R., Ai, Q.H., Mai, K.S., 2011. Ontogenic development of digestive enzyme activities in juvenile soft-shelled turtle (Pelodiscus sinensis) under cultured conditions. Frontiers of Agriculture in China5, 624-630. (通讯作者)
Asino, H., Ai, Q.H., Mai, K.S., 2010. Evaluation of Enteromorpha prolifera as a feed component in large yellow croaker (Pseudosciaena crocea, Richardson, 1846) diets Aquaculture Research 1-9. (通讯作者)
Liu, F., Ai, Q.H., Mai, K.S., Tan, B.P., Ma, H.M., Xu, W., Zhang, W.B., LiuFu, Z.G., 2008. Effects of Dietary Binders on Survival and Growth Performance of Post Larval Tongue Sole, Cynoglossus semilaevis (Günther). Journal of the World Aquaculture Society 39, 500-509. (通讯作者)
Xie, F.J., Ai, Q.H., Mai, K.S., Xu, W., Wang, X.J., 2011. Dietary lysine requirement of large yellow croaker (Pseudosciaena crocea, Richardson 1846) larvae. Aquaculture Research(通讯作者)
Liu X.W., Mai, K.S., Ai, Q.H., Wang X.J., Liufu Z.G., Zhang Y.J., 2013. Effects of Protein and Lipid Levels in Practical Diets on Growthand Body Composition of Tongue Sole, Cynoglossus semilaevis Gunther. Journal of the World Aquaculture Society 44, 96-104.
Zhang Y.J., Chen W., Mai, K.S., Ai, Q.H., Xu W., Zhang W.B., 2013. In vitro assay for evaluating the effects of three anti-nutritional factors on the primary-cultured intestinal epithelial cells isolated from Japanese flounder, Paralichthys olivaceus. Aquaculture Research, 1–10.
Cheng Z.Y., Mai, K.S., Ai, Q.H., Li Y., 2013. Effects of Dietary Pregelatinized Corn Starch on Growth, Apparent Digestibility, and Digestive Enzyme Activity of Large Yellow Croaker Fingerlings (Pseudosciaena crocea). Israeli Journal of Aquaculture -Bamidgeh, 65.
Cui L.Q., Xu W., Ai, Q.H., Wang D.F., Mai, K.S., 2013. Effects of dietary chitosan oligosaccharide complex with rare earth on growth performance and innate immune response of turbot, Scophthalmus maximus L. Aquaculture Research 44, 1-8.
Li M.Z., Mai, K.S., He G., Ai, Q.H., Zhang W.B., Xu W., Wang J., Liufu Z.G., Zhang Y.J., Zhou H.H., 2013. Characterization of two Δ 5 fatty acyl desaturases in abalone (Haliotis discus hannai Ino). Aquaculture 416, 48–56.
Li M.Z., Mai, K.S., Ai, Q.H., He G., Xu W., Zhang W.B., Zhang Y.J., Zhou H.H., 2013. Effects of dietary grape seed oil and linseed oil on growth, muscle fatty acid composition and expression of putative Δ5 fatty acyl desaturase in abalone Haliotis discus hannai Ino. Aquaculture 406, 105–114.
Peng M., Xu W., Ai, Q.H., Mai, K.S., Liufu Z.G., Zhang K.K., 2013. Effects of nucleotide supplementation on growth, immune responsesand intestinal morphology in juvenile turbot fed diets with gradedlevels of soybean meal (Scophthalmus maximus L.). Aquaculture 392, 51–58.
Li J.Q., Tan B.P., Mai, K.S., Ai, Q.H., Zhang W.B., Xu W., Liufu Z.G., Ma H.M., 2006. Comparative study between probiotic bacterium Arthrobacter XE-7 and chloramphenicol on protection of Penaeus chinensis post-larvae from pathogenic vibrios. Aquaculture 253, 140–147.
Mai, K.S., Wan J.L., Ai, Q.H., Xu W., Liufu Z.G., Zhang L., Zhang C.X., Li H.T., 2006. Dietary methionine requirement of large yellow croaker, Pseudosciaena crocea R. Aquaculture 258, 535–542.
Mai, K.S., Zhang L., Ai, Q.H., Duan Q.Y., Zhang C.X., Li H.T., Wan J.L., Liufu Z.G.,2006. Dietary lysine requirement of juvenile Japanese seabass, Lateolabrax japonicus. Aquaculture 253, 564–572.
Deng J.M., Mai, K.S., Ai, Q.H., Zhang W.B., Wang X.J., Xu W., Liufu Z.G., 2006. Effects of replacing fish meal with soy protein concentrate on feed intake and growth of juvenile Japanese flounder, Paralichthys olivaceus. Aquaculture 258, 503–513.
Zhang, C.X., Ai, Q.H., Mai, K.S., Tan, B.P., Li, H.T., Zhang, L., 2008. Dietary lysine requirement of large yellow croaker, Pseudosciaena crocea R. Aquaculture 283, 123-127.
Xu, W., Mai, K.S., Ai, Q.H., Tan, B.P., Zhang, W.B., Ma, H.M., Liufu, Z.G., 2011. Influence of 18:2n-6/20:5n-3 ratio in diets on growth and fatty acid composition of juvenile abalone, Haliotis discus hannai Ino. Aquaculture Nutrition 17, 346-351.
Mai, K.S., Xiao, L.D., Ai, Q.H., Wang, X.J., Xu, W., Zhang, W.B., Liufu, Z.G., Ren, M.C., 2009. Dietary choline requirement for juvenile cobia, Rachycentron canadum. Aquaculture 289, 124-128.
Deng, J.M., Mai, K.S., Ai, Q.H., Zhang, W.B., Tan, B.P., Xu, W., Liufu, Z.G., 2010. Alternative protein sources in diets for Japanese flounder Paralichthys olivaceus (Temminck and Schlegel): II. Effects on nutrient digestibility and digestive enzyme activity. Aquaculture Research 41(6), 861-870.
Deng, J., Mai, K.S., Ai, Q.H., Zhang, W., Wang, X., Tan, B., Xu, W., Liufu, Z., Ma, H., 2010. Interactive effects of dietary cholesterol and protein sources on growth performance and cholesterol metabolism of Japanese flounder (Paralichthys olivaceus). Aquaculture 16,419-429.
Zhang, L., Mai, K.S., Ai, Q.H., Duan, Q.Y., Zhang, C.X., Li, H.T., Tan, B.P., 2008. Use of a compound protein source as a replacement for fish meal in diets of large yellow croaker, Pseudosciaena crocea R. Aquaculture 39, 83-90.
Liu, K., Wang, X.J., Ai, Q.H., Mai, K.S., Zhang W.B., 2010. Dietary selenium requirement for juvenile cobia, Rachycentron canadum L. Aquaculture Research 41, 594-601.
Wu, C.L. Mai, K.S.,Zhang, W.B.,Ai, Q.H., Xu, W., Wang, X.J., Ma, H.M.,Liufu, Z.G., 2010. Molecular cloning, characterization and mRNA expression of selenium-dependent glutathione peroxidase from abalone haliotis discus hanai Ino in response to dietary selenium, zinc and iron. Comparative Biochemistary and Physiology C-Toxicology and Pharmacology 152(2), 121-132.
Hu, Y., Tan, B.P., Mai, K.S., Ai, Q.H., Zhang, L., Zheng, S.X., 2011. Effects of dietary menhaden oil, soybean oil and soybean lecithin oil at different ratios on growth, body composition and blood chemistry of juvenile Litopenaeus vannamei. Aquaculture International19, 459-473.
Zhang, Y.J., Mai, K.S., Ma, H.M., Ai, Q.H., Zhang, W.B., Xu, W., 2011. Rearing in intermediate salinity enhances immunity and disease-resistance of turbot (Scophthalmus maximus L.). Acta Oceanologica Sinica30, 122-128.
Zhao, Y.C., Ma, H.M., Zhang, W.B., Ai, Q.H., Mai, K.S., Xu, W., Wang, X.J., Liufu, Z.G., 2011. Effects of dietary β-glucan on the growth, immune responses and resistance of sea cucumber, Apostichopus japonicus against Vibrio splendidus infection. Aquaculture315, 269-274.
Hu, Y., Tan, B. P., Mai, K.S., Ai, Q.H., Zheng, S.,Cheng, K., 2007. Growth and body composition of juvenile white shrimp, Litopenaeus vannamei, fed different ratios of dietary protein to energy. Aquaculture Nutrition 14(6), 499-506.
Wang, W.F., Mai, K.S.,Zhang, W.B., Ai, Q.H.,Yao, C. F., Li, H.T., Liufu, Z.G., 2009. Effects of dietary copper on survival, growth and immune reponse of juvenile abalone, haliotis discushannai Ino. Aquaculture 297, 122-127.
Li, J., Zhang, L., Mai, K.S., Ai, Q.H., Wan, J., Zhang, C., Zhang, J., 2009. Estimation of dietary biotin requirement of Japanese seabass, lateolabrax japonicas. Aquaculture 16(3), 231-236.
Li, J., Zhang, L., Mai, K.S., Ai, Q.H., Zhang, C.X., Li, H,T., Duan, Q.Y.,Ma, H.M., Zhang, L., Zheng, S.X., 2010. Potential of several protein sources as fish meal substitutes in diets for large yellow croaker pseudosciaena crocea R. Journal of the world aquaculture society. 41(2), 278-283.
Li, J. Q., Tan, B. P., Mai, K.S., Ai, Q.H., Zhang, W.B., Liufu, Z.G.,Xu, W., 2008. Immune responses and resistance against vibrio parahaemolyticus induced by probiotic bacterium arthrobacter XE-7 in pacific white shrimp, litopenaeus vannamei. Journal of the World Aquaculture Society 39(4), 477-489
Zhang, L., Mai, K.S., Tan, B. P., Ai, Q.H.,Qi, C.Z., Xu, W., Zhang, W.B., Liufu, Z.G., Wang, X. J., Ma, H. M., 2008. Effects of dietary administration of probiotic halomonas sp B12 on the Intestinal microflora, Immunological Parameters, and midgut histological structure of shrimp, fenneropenaeus chinensis. Journal of the World Aquaculture Society 40(1), 58-66.
Wang, W.F., Mai, K.S., Zhang, W.B., Xu, W., Ai, Q.H., Liufu, Z.G., Li, H.T., 2012. Dietary selenium requirement and its toxicity in juvenile abalone Haliotis discus hannai Ino. Aquaculture330-333, 42-46.
Chen, X.R. Mai, K.S.,Zhang, W.B., Wang, X.J., Ai, Q.H., Xu, W., Liufu, Z.G., Ma, H.M., Tan, B. P., 2010. Effects of dietary glycyrrhizin on growth and nonspecific immunity of white shrimp, litopenaeus vannamei. Journal of the World Aquaculture Society 41(5), 665-674.
Gu, M., Ma, H.M., Mai, K.S.,Zhang, W.B., Ai, Q.H., Wang, X.J., Bai, N., 2010. Immune response of sea cucumber aposichopus japonicas coelomocytes to several immunosimulants in vitro. Aquaculture 306(1-4), 49-56.
Zhang, Q., Tan, B.P., Mai, K.S., Zhang, W.B., Ma, H.M., Ai, Q.H., Wang, X.J., Liufu, Z.G., 2011. Dietary administration of Bacillus (B. licheniformis and B. subtilis) and isomaltooligosaccharide influences the intestinal microflora, immunological parameters and resistance against Vibrio alginolyticus in shrimp, Penaeus japonicus (Decapoda: Penaeidae). Aquaculture Research42, 943-952.
Zhang, W.B., Mai, K.S., Xu, W., Liufu, Z.G., Tan, B. P., Ai, Q.H., Ma, H.M., Wang, X.J., 2008. Effects of dietary guaiacol on shell biomineralization of juvenile abalone haliotis discus hannai, Ino. Aquaculture Research 39(9), 954-961.
Chen, J.H., Mai, K.S., Ma, H.M., Wang, X.J., Deng, D., Liu, X.W., Xu, W., Liufu, Z.G., Zhang, W.B., Tan, B.P., Ai, Q.H., 2007. Effects of dissolved oxygen on survival and immune response of scallop (Chlamys farreri Jones et Preston). Fish and Shellfish Immunology 22, 272-281.
Zeng, D., Mai, K.S., Ai, Q.H., Milley, J.E., Lall, S.P., 2010. Lipid and fatty acid compositions of cod (Gadus morhua), haddock (Melanogrammus aeglefinus) and halibut (Hippoglossus hippoglossus). Journal of Ocean University of China (English Edition) 9, 381-388.
Deng, J.M., Mai, K.S., Ai, Q.H., Zhang, W.B., 2007. Effects of soybean oligosaccharides on lipid metabolism of Japanese flounder (Paralichthys olivaceus Temminck et Schlegel) fed animal or plant protein source-based diets. Frontiers of Agriculture in China1,315-323.
Li, H.T., Mai, K.S., Ai, Q.H., Zhang, C.X., Zhang, L., 2009. Effects of dietary squid viscera meal on growth and cadmium accumulation in tissues of large yellow croaker, Pseudosciaena crocea R.Frontiers of Agriculture in China3, 78-83.
Zhao, Y.C., Mai, K.S., Xu, W., Zhang, W.B., Ai, Q.H., 2011. Influence of dietary probiotic Bacillus TC22 and Prebiotic fructooligosaccharide on growth, immune responses and disease resistance against Vibrio splendidus infection in sea cucumber Apostichopus japonicus. Journal of Ocean University of China (English Edition)10, 293-300.
Wang, W.F., Mai, K.S., Zhang, W.B., Xu, W., Ai, Q.H., et al., 2009. Effects of dietary carbohydrates sources on lipids compositions in abalone, Haliotis discus hannai Ino. Journal of Ocean University of China (English Edition)8, 254-258.
